Acetic acid, [(4-methylphenyl)sulfonyl]-, 8-quinolinyl ester

Base Information

• Chemical Name: Acetic acid, [(4-methylphenyl)sulfonyl]-, 8-quinolinyl ester
• CAS No.: 141649-58-3
• Molecular Formula: C₁₈H₁₅NO₄S
• Molecular Weight: 341.387
• Mol file: 141649-58-3.mol

Synonyms:

Chemical Property of Acetic acid, [(4-methylphenyl)sulfonyl]-, 8-quinolinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid, [(4-methylphenyl)sulfonyl]-, 8-quinolinyl ester

There total 3 articles about Acetic acid, [(4-methylphenyl)sulfonyl]-, 8-quinolinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

p-Tolylsulfanyl-acetic acid quinolin-8-yl ester (141649-50-5) → (Toluene-4-sulfonyl)-acetic acid quinolin-8-yl ester (141649-58-3)

Guidance literature:

With dihydrogen peroxide; acetic acid; for 72h; Ambient temperature;

DOI:10.1135/cccc19921547

Reference yield:

8-quinolinol (148-24-3,24804-14-6) → (Toluene-4-sulfonyl)-acetic acid quinolin-8-yl ester (141649-58-3)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / 2 h / Ambient temperature

2: 73 percent / benzene / 8 h / Heating

3: 70 percent / glacial CH₃COOH, H₂O₂ / 72 h / Ambient temperature

With pyridine; dihydrogen peroxide; acetic acid; In benzene;

DOI:10.1135/cccc19921547

Reference yield:

8-quinolyl-α-chloroacetate (5568-49-0) → (Toluene-4-sulfonyl)-acetic acid quinolin-8-yl ester (141649-58-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / benzene / 8 h / Heating

2: 70 percent / glacial CH₃COOH, H₂O₂ / 72 h / Ambient temperature

With dihydrogen peroxide; acetic acid; In benzene;

DOI:10.1135/cccc19921547

upstream raw materials:

p-Tolylsulfanyl-acetic acid quinolin-8-yl ester

8-quinolinol

8-quinolyl-α-chloroacetate