2,2',4',5'-tetrachloroacetophenone

Base Information

• Chemical Name: 2,2',4',5'-tetrachloroacetophenone
• CAS No.: 1201-42-9
• Molecular Formula: C8H4 Cl4 O
• Molecular Weight: 257.931
• Mol file: 1201-42-9.mol

Synonyms:Acetophenone,2,2',4',5'-tetrachloro- (7CI,8CI); 2,2',4',5'-Tetrachloroacetophenone;2,4,5-Trichlorophenacyl chloride; a,2,4,5-Tetrachloroacetophenone

Chemical Property of 2,2',4',5'-tetrachloroacetophenone

Chemical Property:

• Vapor Pressure: 0.000114mmHg at 25°C
• Melting Point: 62.5-63.0 °C
• Boiling Point: 336.2°Cat760mmHg
• Flash Point: 141.8°C
• PSA: 17.07000
• Density: 1.533g/cm³
• LogP: 4.06830

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloro-1-(2,4,5-trichlorophenyl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2',4',5'-tetrachloroacetophenone

There total 1 articles about 2,2',4',5'-tetrachloroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-chloro-1-(2,4,5-trichloro-phenyl)-ethanone (1201-42-9)

Guidance literature:

/BRN= 956819/, CH2Cl-COCl, AlCl3;

Reference yield: 91.0%

2-chloro-1-(2,4,5-trichloro-phenyl)-ethanone (1201-42-9) + 2-sulfanyl-1,3-benzoxazole (2382-96-9,118090-08-7) → 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(2,4,5-trichlorophenyl)ethanone

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 - 22 ℃; for 1h;

DOI:10.3390/molecules26165008

Reference yield:

2-chloro-1-(2,4,5-trichloro-phenyl)-ethanone (1201-42-9) + 2-sulfanyl-1,3-benzoxazole (2382-96-9,118090-08-7) → 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(2,4,5-trichlorophenyl)ethanol

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 1 h / 20 - 22 °C

2: sodium tetrahydroborate / methanol / 0.5 h / 0 - 3 °C

With sodium tetrahydroborate; potassium carbonate; In methanol; acetonitrile;

DOI:10.3390/molecules26165008

Downstream raw materials:

(4-amino-2-methylsulfanyl-thiazol-5-yl)-(2,4,5-trichloro-phenyl)-methanone

2,4,5,α-Tetrachlor-α,α-dibromacetophenon

Phosphoric acid (Z)-2-bromo-2-chloro-1-(2,4,5-trichloro-phenyl)-vinyl ester dimethyl ester

Phosphoric acid (Z)-2-bromo-2-chloro-1-(2,4,5-trichloro-phenyl)-vinyl ester diethyl ester