[4-(2-PHENYLETHYL)PHENYL]AMINEHYDROCHLORIDE

Base Information

• Chemical Name: [4-(2-PHENYLETHYL)PHENYL]AMINEHYDROCHLORIDE
• CAS No.: 71845-20-0
• Molecular Formula: C14H15N
• Molecular Weight: 197.2756
• Hs Code.: 2921499090
• Mol file: 71845-20-0.mol

Synonyms:4-(2-phenylethyl)aniline hydrochloride;4-Phenethylaniline HCl;p-(2-phenylethyl)aniline hydrochloride;bibenzyl-4-ylamine,hydrochloride;Bibenzyl-4-ylamin,Hydrochlorid;[4-(2-Phenylethyl)phenyl]amine hydrochloride;

Chemical Property of [4-(2-PHENYLETHYL)PHENYL]AMINEHYDROCHLORIDE

Chemical Property:

• Boiling Point: 320.1°Cat760mmHg
• Flash Point: 153.9°C
• PSA: 26.02000
• Density: 1.065g/cm³
• LogP: 4.43720
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99%min ^*data from raw suppliers

[4-(2-Phenylethyl)phenyl]aminehydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [4-(2-PHENYLETHYL)PHENYL]AMINEHYDROCHLORIDE

There total 2 articles about [4-(2-PHENYLETHYL)PHENYL]AMINEHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.9%

4-nitrostilbene (1694-20-8,4003-94-5,6624-53-9,101977-34-8) → 4-(β-phenylethyl)aniline hydrochloride (71845-20-0)

Guidance literature:

4-nitrostilbene; With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h;

With hydrogenchloride; In dichloromethane; water;

DOI:10.1016/j.bmc.2010.11.028

Reference yield:

trans-4-nitrostilbene (1694-20-8) + ethereal HCl → 4-(β-phenylethyl)aniline hydrochloride (71845-20-0)

Guidance literature:

palladium-carbon; In ethanol;

Reference yield: 5.3%

4-(β-phenylethyl)aniline hydrochloride (71845-20-0) + Diethyl ketomalonate (609-09-6) → 5-(2-phenylethyl)isatin (1263998-59-9)

Guidance literature:

4-(β-phenylethyl)aniline hydrochloride; Diethyl ketomalonate; With acetic acid; at 110 - 120 ℃; for 8h;

With potassium hydroxide; at 120 ℃; for 18h; pH=11;

DOI:10.1016/j.bmc.2010.11.028

upstream raw materials:

trans-4-nitrostilbene

4-nitrostilbene

Downstream raw materials:

5-(2-phenylethyl)isatin

5-(2-phenylethyl)-1H-indole

Refernces

• 1、 -. "5-HT-1D receptor ligands". . . Retrieved 2008/06/13.