(-)-Stemonine

Base Information

Chemical Name:(-)-Stemonine
CAS No.:27498-90-4
Molecular Formula:C₁₇H₂₅NO₄
Molecular Weight:307.39
Hs Code.:
Mol file:27498-90-4.mol

Synonyms:2H-Furo[3,2-c]pyrrolo[1,2-a]azepin-2-one,decahydro-1-methyl-8-(tetrahydro-4-methyl-5-oxo-2-furanyl)-, [1S-[1a,3ab,8a(2R*,4R*),10aa,10ba]]-; Stemonine (C17 alkaloid)(8CI); (-)-Stemonine; Stemonine

Suppliers and Price of (-)-Stemonine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (-)-Stemonine

Chemical Property:

PSA：55.84000
LogP:1.68040

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (-)-Stemonine

There total 42 articles about (-)-Stemonine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 14,15-dehydrostemonine

: 27498-90-4
stemonine

Guidance literature:: With Rh/alumina; hydrogen; In ethanol; at 20 ℃; for 3h; under 760.051 Torr;
DOI:10.1021/jacs.7b10944

Reference yield: 68.0%

: 609817-44-9
(3S,5S)-5-((1S,3aR,7S,9aS,9bR)-2-Hydroxy-1-methyl-decahydro-3-oxa-6a-aza-cyclopenta[e]azulen-7-yl)-3-methyl-dihydro-furan-2-one

: 27498-90-4
stemonine

Guidance literature:: With chromium(VI) oxide; sulfuric acid; In tetrahydrofuran; water; acetone; at 20 ℃;
DOI:10.1021/ol035368q

Reference yield:

: 794528-61-3
(1S,3aR,10aS,10bR)-1-methyloctahydro-2H-furo[3,2-c]pyrrolo[1,2-a]azepine-2,8(1H)-dione

: 27498-90-4
stemonine

Guidance literature:: Multi-step reaction with 3 steps

1: bis(triphenylphosphine)iridium(I) carbonyl chloride; 1,1,3,3-Tetramethyldisiloxane / toluene / 1 h / 20 °C / Inert atmosphere

2: ortho-nitrobenzoic acid / toluene; acetonitrile / 24 h / 20 °C / Inert atmosphere

3: hydrogen; Rh/alumina / ethanol / 3 h / 20 °C / 760.05 Torr

With bis(triphenylphosphine)iridium(I) carbonyl chloride; 1,1,3,3-Tetramethyldisiloxane; ortho-nitrobenzoic acid; Rh/alumina; hydrogen; In ethanol; toluene; acetonitrile;
DOI:10.1021/jacs.7b10944