Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate

Base Information Edit

Chemical Name:Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate
CAS No.:21165-77-5
Molecular Formula:C18H19ClN2O6S
Molecular Weight:426.878
Hs Code.:2935009090
European Community (EC) Number:244-254-2
UNII:J05PEU2DTT
DSSTox Substance ID:DTXSID60175405
Nikkaji Number:J226.156A
Wikidata:Q83045738
Mol file:21165-77-5.mol

Synonyms:21165-77-5;Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate;Glibenclamide Impurity B;methyl N-[4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonylcarbamate;J05PEU2DTT;METHYL N-[4-[2-[(5-CHLORO-2-METHOXY-BENZOYL)AMINO]ETHYL]PHENYL]SULFONYLCARBAMATE;Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)carbamate;Methyl [[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulphonyl]carbamate;Carbamic acid, ((4-(2-((5-chloro-2-methoxybenzoyl)amino)ethyl)phenyl)sulfonyl)-, methyl ester;EINECS 244-254-2;UNII-J05PEU2DTT;DTXSID60175405;WAA16577;CS-0166574;Methyl N-4[2-(5-Chloro-2-Methoxybenzamido)Ethyl]Benzenesulfonylcarbamate;[4-[2-(2-Methoxy-5-chlorobenzoylamino)ethyl]phenylsulfonyl]carbamic acid methyl ester;CARBAMIC ACID, ((P-(2-(5-CHLORO-O-ANISAMIDO)ETHYL)PHENYL)SULFONYL)-, METHYL ESTER;CARBAMIC ACID, N-((4-(2-((5-CHLORO-2-METHOXYBENZOYL)AMINO)ETHYL)PHENYL)SULFONYL)-, METHYL ESTER;Glyburide Related Compound B (25 mg) (methyl-[[4-[2-[(5-chloro-2-methoxybenzoyl)-amino]ethyl]phenyl]sulfonyl]carbamate) (AS);Methyl N-4[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonylcarbamate (Glibenclamide EP Impurity B);METHYL-((4-(2-((5-CHLORO-2-METHOXYBENZOYL)-AMINO)ETHYL)PHENYL)SULFONYL)CARBAMATE (AS)

Suppliers and Price of Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamicAcidMethylEster
25mg
$ 630.00

Sigma-Aldrich
Glibenclamide impurity B
25mg
$ 1260.00

Sigma-Aldrich
Glibenclamide impurity B European Pharmacopoeia (EP) Reference Standard
y0000242
$ 190.00

Total 15 raw suppliers

Chemical Property of Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate Edit

Chemical Property:

Melting Point:189-191℃
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：126.16000
Density:1.361g/cm³
LogP:4.22580
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:426.0652352
Heavy Atom Count:28
Complexity:631

Purity/Quality:

97% ^*data from raw suppliers

N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)OC
Uses N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester is an impurity in the synthesis of Gyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.

Technology Process of Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate

There total 1 articles about Methyl N-(4-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulphonyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: