N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide

Base Information

Chemical Name:N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide
CAS No.:142312-10-5
Molecular Formula:C15H11N5O
Molecular Weight:277.285
Hs Code.:
DSSTox Substance ID:DTXSID90565638
Wikidata:Q82450846

Synonyms:142312-10-5;N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide;N-[(5,6-Dicyanopyrazin-2-yl)methyl]-N-phenylacetamide;DTXSID90565638

Suppliers and Price of N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:277.09635999
Heavy Atom Count:21
Complexity:467

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N(CC1=CN=C(C(=N1)C#N)C#N)C2=CC=CC=C2

Technology Process of N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide

There total 3 articles about N-((5,6-Dicyanopyrazin-2-yl)methyl)-N-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 13481-25-9
pyrazine-2,3-dicarbonitrile

: 579-98-6,116306-61-7
N-acetyl-N-phenylglycine

: 142312-10-5
5-(N-acetylanilino)methylpyrazine-2,3-dicarbonitrile

: 142312-11-6
N-{3-[(Acetyl-phenyl-amino)-methyl]-5,6-dicyano-pyrazin-2-ylmethyl}-N-phenyl-acetamide

: 103-84-4
Acetanilid

Guidance literature:: With ammonium persulfate; silver nitrate; In water; acetonitrile; at 80 - 90 ℃; for 0.666667h;
DOI:10.3987/COM-91-5931

Reference yield: 15.0%

: 13481-25-9
pyrazine-2,3-dicarbonitrile

: 160350-45-8
N-Phenyl-N-trimethylsilanylmethyl-acetamide

: 142312-10-5
5-(N-acetylanilino)methylpyrazine-2,3-dicarbonitrile

: N-(3-Cyano-pyrazin-2-ylmethyl)-N-phenyl-acetamide

Guidance literature:: In acetonitrile; Irradiation;

Reference yield:

: 103-84-4
Acetanilid

: 142312-10-5
5-(N-acetylanilino)methylpyrazine-2,3-dicarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH, 2.) tris<2-(2-methoxyethoxy)ethyl>amine, NaI / 1.) THF, reflux, 1 h, 2.) THF, reflux, 24 h

2: 8 percent / acetonitrile / Irradiation

With Tris(3,6-dioxaheptyl)amine; sodium hydride; sodium iodide; In acetonitrile;