Technology Process of 2-Penten-1-ol,
5-[1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,5-cyclohexadien-1-yl
]-2-iodo-, (Z)-
There total 6 articles about 2-Penten-1-ol,
5-[1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,5-cyclohexadien-1-yl
]-2-iodo-, (Z)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1) LDA / 1) THF, HMPA, -78 deg C, 2) 0 deg C
2: 100 percent / LiAlH4 / diethyl ether / -40 °C
3: 100 percent / imidazole / dimethylformamide
4: 1) EtMgBr / 1) THF, 2) -30 deg C
5: NaBH4 / methanol / 0 °C
6: 1) n-BuLi, DIBAH, 2) I2 / 1) Et2O, 35 deg C, 36 h 2) -78 deg C
With
1H-imidazole; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; ethylmagnesium bromide; iodine; diisobutylaluminium hydride; lithium diisopropyl amide;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)92251-2
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / imidazole / dimethylformamide
2: 1) EtMgBr / 1) THF, 2) -30 deg C
3: NaBH4 / methanol / 0 °C
4: 1) n-BuLi, DIBAH, 2) I2 / 1) Et2O, 35 deg C, 36 h 2) -78 deg C
With
1H-imidazole; sodium tetrahydroborate; n-butyllithium; ethylmagnesium bromide; iodine; diisobutylaluminium hydride;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)92251-2
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / LiAlH4 / diethyl ether / -40 °C
2: 100 percent / imidazole / dimethylformamide
3: 1) EtMgBr / 1) THF, 2) -30 deg C
4: NaBH4 / methanol / 0 °C
5: 1) n-BuLi, DIBAH, 2) I2 / 1) Et2O, 35 deg C, 36 h 2) -78 deg C
With
1H-imidazole; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; ethylmagnesium bromide; iodine; diisobutylaluminium hydride;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)92251-2
