Propanimidothioic acid, N-hydroxy-2-(hydroxyimino)-, phenyl ester

Base Information

• Chemical Name: Propanimidothioic acid, N-hydroxy-2-(hydroxyimino)-, phenyl ester
• CAS No.: 142764-04-3
• Molecular Formula: C9H10N2O2S
• Molecular Weight: 210.257
• Mol file: 142764-04-3.mol

Synonyms:

Chemical Property of Propanimidothioic acid, N-hydroxy-2-(hydroxyimino)-, phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanimidothioic acid, N-hydroxy-2-(hydroxyimino)-, phenyl ester

There total 1 articles about Propanimidothioic acid, N-hydroxy-2-(hydroxyimino)-, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

anti-1-methyl-2-chloroglyoxime (17019-19-1) + thiophenol (108-98-5) → N-Hydroxy-2-[(E)-hydroxyimino]-thiopropionimidic acid phenyl ester (142764-04-3)

Guidance literature:

With triethylamine; In diethyl ether; for 1h; Ambient temperature;

DOI:10.1021/jm00095a028

Reference yield: 40.0%

N-Hydroxy-2-[(E)-hydroxyimino]-thiopropionimidic acid phenyl ester (142764-04-3) → 4-methyl-3-phenylthiofuroxan (49739-37-9) + 3-methyl-4-(phenylthio)furoxan (49739-36-8)

Guidance literature:

With dinitrogen tetraoxide; In diethyl ether; at 0 - 20 ℃; for 17h;

DOI:10.1021/jm00095a028

Reference yield:

N-Hydroxy-2-[(E)-hydroxyimino]-thiopropionimidic acid phenyl ester (142764-04-3) → 3-benzenesulfonyl-4-methyl-furazan (49739-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) N₂O₂, 2.) trimethyl phosphite / 1.) ether, 0-20 deg C, 17 h

2: 95 percent / 81percent H₂O₂ / trifluoroacetic acid / 1 h

With N-oxo-N-nitrosoamine; dihydrogen peroxide; phosphorous acid trimethyl ester; In trifluoroacetic acid;

DOI:10.1021/jm00095a028

upstream raw materials:

anti-1-methyl-2-chloroglyoxime

thiophenol

Downstream raw materials:

3-methyl-4-phenylsulfanyl-furazan

4-methyl-3-phenylthiofuroxan

3-methyl-4-(phenylthio)furoxan

3-methyl-4-phenylsulphonylfuroxan