2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride

Base Information

Chemical Name:2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride
CAS No.:38946-46-2
Molecular Formula:C11H16INO
Molecular Weight:341.62
Hs Code.:
ChEMBL ID:CHEMBL537476
DSSTox Substance ID:DTXSID20959788
NSC Number:298269

Synonyms:2-aminomethyl-4-butyl-6-iodophenyl;2-aminomethyl-4-t-butyl-6-iodophenol;2-aminomethyl-4-t-butyl-6-iodophenol hydrochloride;MK 447;MK-447

Suppliers and Price of 2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride

Chemical Property:

Vapor Pressure:0.000412mmHg at 25°C
Boiling Point:306.9°Cat760mmHg
Flash Point:139.4°C
Density:1.552g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:341.00434
Heavy Atom Count:15
Complexity:190

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=C(C(=C1)I)O)CN.Cl

Technology Process of 2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride

There total 5 articles about 2-Aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 63712-11-8
2-aminomethyl-4-tert-butyl-phenol; hydrochloride

: 38946-46-2
2-aminomethyl-4-(1,1-dimethyl ethyl)-6-iodophenol hydrochloride

Guidance literature:: With hydrogenchloride; Iodine monochloride; In water; at 20 ℃; for 2h;
DOI:10.1021/jm00186a024

Reference yield:

: 98-54-4
para-tert-butylphenol

: 38946-46-2
2-aminomethyl-4-(1,1-dimethyl ethyl)-6-iodophenol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄, HOAc / 16 h / 22 °C

2: ICl, 3 N HCl / 2 h / 20 °C

3: conc. HCl / ethanol / 1.5 h / Heating

With hydrogenchloride; sulfuric acid; Iodine monochloride; acetic acid; In ethanol;
DOI:10.1021/jm00186a024

Reference yield:

: 869953-38-8
N-(5-tert-Butyl-2-hydroxy-benzyl)-2-chloro-acetamide

: 38946-46-2
2-aminomethyl-4-(1,1-dimethyl ethyl)-6-iodophenol hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: ICl, 3 N HCl / 2 h / 20 °C

2: conc. HCl / ethanol / 1.5 h / Heating

With hydrogenchloride; Iodine monochloride; In ethanol;
DOI:10.1021/jm00186a024