prothracarcin

Base Information

Chemical Name:prothracarcin
CAS No.:81542-99-6
Molecular Formula:C₁₄H₁₄N₂O
Molecular Weight:226.278
Hs Code.:
Mol file:81542-99-6.mol

Synonyms:Benzene,[2-(propylthio)ethenyl];(Z)-propyl(styryl)sulfane;(Z)-prothracarcin;(Z)-1-propylthio-2-phenylethylene;(E)-prothracarcin;

Suppliers and Price of prothracarcin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
PROTHRACARCIN 95.00%
5MG
$ 496.16

Total 5 raw suppliers

Chemical Property of prothracarcin

Chemical Property:

Vapor Pressure:1.13E-07mmHg at 25°C
Boiling Point:432.2°Cat760mmHg
Flash Point:215.2°C
PSA：32.67000
Density:1.22g/cm³
LogP:1.93680

Purity/Quality:

>98% ^*data from raw suppliers

PROTHRACARCIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of prothracarcin

There total 29 articles about prothracarcin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S,E)-2-ethylidene-10-{[2-(trimethylsilyl)ethoxy]methyl}-2,3-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-5,11(10H,11aH)-dione

: 81542-99-6
(E)-prothracarcin

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 20 ℃;
DOI:10.1055/s-0034-1378877

Reference yield:

: 615-43-0
2-iodophenylamine

: 81542-99-6
(E)-prothracarcin

Guidance literature:: Multi-step reaction with 11 steps

2: 92 percent / diisopropylethylamine / CH₂Cl₂ / Ambient temperature

3: 95 percent / NaH / tetrahydrofuran / -30 °C

4: 87 percent / NH₃ / methanol

5: 90 percent / n-Bu₃N, PPh₃ / Pd(OAc)2 / toluene / 48 h / 110 °C / 3800 Torr

6: 65 percent / HCl / methanol / 12 h / 50 °C

7: molecular sieve, PCC / CH₂Cl₂ / 2 h / Ambient temperature

8: 1.) t-BuOK / 1.) THF, 20 min; 2.) THF, room temperature, 1 h

9: 30 percent / MCPBA, NaHCO₃ / not given

10: 1.) Li, ClPPh₂ / 1.) THF; 2.) THF

11: 1.) NaBH₄; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene

With hydrogenchloride; sodium tetrahydroborate; molecular sieve; tributyl-amine; potassium tert-butylate; ammonia; silica gel; lithium; sodium hydride; sodium hydrogencarbonate; chloro-diphenylphosphine; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; pyridinium chlorochromate; palladium diacetate; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1016/S0040-4020(01)87534-7

Reference yield:

: (2S,4R)-4-Methoxymethoxy-pyrrolidine-2-carboxylic acid (2-bromo-phenyl)-methoxymethyl-amide

: 81542-99-6
(E)-prothracarcin

Guidance literature:: Multi-step reaction with 7 steps

1: 49 percent / n-Bu₃N, PPh₃ / Pd(OAc)2 / toluene / 48 h / 110 °C / 3800 Torr

2: 65 percent / HCl / methanol / 12 h / 50 °C

3: molecular sieve, PCC / CH₂Cl₂ / 2 h / Ambient temperature

4: 1.) t-BuOK / 1.) THF, 20 min; 2.) THF, room temperature, 1 h

5: 30 percent / MCPBA, NaHCO₃ / not given

6: 1.) Li, ClPPh₂ / 1.) THF; 2.) THF

7: 1.) NaBH₄; 2.) silica gel / 1.) EtOH, 0 degC, 3 h; 2.) room temperature, 30 min, benzene

With hydrogenchloride; sodium tetrahydroborate; molecular sieve; tributyl-amine; potassium tert-butylate; silica gel; lithium; sodium hydrogencarbonate; chloro-diphenylphosphine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; pyridinium chlorochromate; palladium diacetate; In methanol; dichloromethane; toluene;
DOI:10.1016/S0040-4020(01)87534-7