diethyl 2-[(5S)-1-azabicyclo[3.1.0]hexan-2-ylidene]propanedioate

Base Information

Chemical Name:diethyl 2-[(5S)-1-azabicyclo[3.1.0]hexan-2-ylidene]propanedioate
CAS No.:142890-28-6
Molecular Formula:C12H17NO4
Molecular Weight:239.271
Hs Code.:
DSSTox Substance ID:DTXSID401138355
Nikkaji Number:J1.892.090E

Synonyms:DTXSID401138355;142890-28-6;Propanedioic acid, 2-(5S)-1-azabicyclo[3.1.0]hex-2-ylidene-, 1,3-diethyl ester

Suppliers and Price of diethyl 2-[(5S)-1-azabicyclo[3.1.0]hexan-2-ylidene]propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of diethyl 2-[(5S)-1-azabicyclo[3.1.0]hexan-2-ylidene]propanedioate

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:239.11575802
Heavy Atom Count:17
Complexity:355

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=C1CCC2N1C2)C(=O)OCC
Isomeric SMILES:CCOC(=O)C(=C1CC[C@@H]2N1C2)C(=O)OCC

Technology Process of diethyl 2-[(5S)-1-azabicyclo[3.1.0]hexan-2-ylidene]propanedioate

There total 1 articles about diethyl 2-[(5S)-1-azabicyclo[3.1.0]hexan-2-ylidene]propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17342-08-4
(S)-Pyroglutaminol

: 142890-28-6
diethyl [(S)-azabicyclo[3.1.0]hex-2-ylidene]malonate

Guidance literature:: Multi-step reaction with 6 steps

1.1: 100 percent / imidazole / dimethylformamide / 12 h / 20 °C

2.1: 97 percent / Lawesson's reagent / toluene / 0.33 h / Heating

3.1: CH₂Cl₂ / 12 h / 20 °C

3.2: 97 percent / KHCO₃ / H₂O; CH₂Cl₂ / 4 h / 20 °C

4.1: 91 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C

5.1: 92 percent / pyridine / CH₂Cl₂ / 12 h / 20 °C

6.1: 34 percent / potassium hydride / tetrahydrofuran / 0.25 h / 20 °C

With Lawessons reagent; pyridine; 1H-imidazole; tetrabutyl ammonium fluoride; potassium hydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; 3.1: Eschenmoser sulfide contraction;
DOI:10.1016/S0040-4020(03)00377-6