2-(3-Bromopyridin-4-YL)acetonitrile

Base Information

Chemical Name:2-(3-Bromopyridin-4-YL)acetonitrile
CAS No.:142892-31-7
Molecular Formula:C7H5BrN2
Molecular Weight:197.03200
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90571890
Nikkaji Number:J465.807H
Wikidata:Q82460077
Mol file:142892-31-7.mol

Synonyms:2-(3-BROMOPYRIDIN-4-YL)ACETONITRILE;142892-31-7;4-Pyridineacetonitrile, 3-bromo-;SCHEMBL360235;DTXSID90571890;(3-Bromopyridin-4-yl)acetonitrile;AKOS006302635;DS-9628;SB53224;CS-0186400;C72683;EN300-1898376;A885085

Suppliers and Price of 2-(3-Bromopyridin-4-YL)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(3-Bromopyridin-4-yl)acetonitrile 98%
250mg
$ 232.00

Crysdot
2-(3-Bromopyridin-4-yl)acetonitrile 98%
1g
$ 579.00

Crysdot
2-(3-Bromopyridin-4-yl)acetonitrile 98%
5g
$ 1738.00

Chemenu
2-(3-bromopyridin-4-yl)acetonitrile 98%
5g
$ 1641.00

Chemenu
2-(3-bromopyridin-4-yl)acetonitrile 98%
1g
$ 547.00

American Custom Chemicals Corporation
2-(3-BROMOPYRIDIN-4-YL)ACETONITRILE 95.00%
5MG
$ 499.20

Ambeed
2-(3-Bromopyridin-4-yl)acetonitrile 98%
1g
$ 431.00

Ambeed
2-(3-Bromopyridin-4-yl)acetonitrile 98%
250mg
$ 170.00

Ambeed
2-(3-Bromopyridin-4-yl)acetonitrile 98%
100mg
$ 108.00

Alichem
3-Bromopyridine-4-acetonitrile
5g
$ 2508.65

Total 7 raw suppliers

Chemical Property of 2-(3-Bromopyridin-4-YL)acetonitrile

Chemical Property:

Vapor Pressure:0.000887mmHg at 25°C
Boiling Point:304.2oC at 760 mmHg
PKA:2.08±0.18(Predicted)
Flash Point:137.8oC
PSA：36.68000
Density:1.575g/cm3
LogP:1.91018
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:195.96361
Heavy Atom Count:10
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

2-(3-Bromopyridin-4-yl)acetonitrile 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC(=C1CC#N)Br

Technology Process of 2-(3-Bromopyridin-4-YL)acetonitrile

There total 2 articles about 2-(3-Bromopyridin-4-YL)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: potassium cyanide

: 3-bromo-4-(chloromethyl)pyridine hydrochloride

: 142892-31-7
2-(3-bromopyridin-4-yl)acetonitrile

Guidance literature:: In ethanol; water; at 100 ℃; for 3h;

Reference yield:

: 143-33-9,25596-52-5
sodium cyanide

: 17117-15-6
3-bromo-4-methyl-1-oxidopyridin-1-ium

: 142892-31-7
2-(3-bromopyridin-4-yl)acetonitrile

: 142892-36-2
3-bromo-4-<1-cyano-2-(3-bromo-4-pyridyl)ethyl>pyridine

Guidance literature:: With p-toluenesulfonyl chloride; Yield given. Multistep reaction. Yields of byproduct given; 1) dioxane, 4h, reflux, 2) EtOH, H₂O, 1h, reflux;
DOI:10.1055/s-1992-26153

Reference yield:

: 103-72-0
phenyl isothiocyanate

: 142892-31-7
2-(3-bromopyridin-4-yl)acetonitrile

: 2-Phenylamino-thieno[2,3-c]pyridine-3-carbonitrile

Guidance literature:: With sodium hydride; methyl iodide; Yield given. Multistep reaction; 1.) DMSO, r.t., 1 h; 110 deg C, 2.) r.t.;
DOI:10.1055/s-1998-2124