Phosphonic acid, (cyclohexylnitromethyl)-, diethyl ester

Base Information

• Chemical Name: Phosphonic acid, (cyclohexylnitromethyl)-, diethyl ester
• CAS No.: 143023-70-5
• Molecular Formula: C11H22NO5P
• Molecular Weight: 279.273
• Mol file: 143023-70-5.mol

Synonyms:

Chemical Property of Phosphonic acid, (cyclohexylnitromethyl)-, diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphonic acid, (cyclohexylnitromethyl)-, diethyl ester

There total 4 articles about Phosphonic acid, (cyclohexylnitromethyl)-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

Cyclohexyl-nitro-acetyl chloride + triethyl phosphite (122-52-1) → diethyl cyclohexyl(nitro)methylphosphonate (143023-70-5)

Guidance literature:

DOI:10.1246/cl.1992.933

Reference yield:

C11H22NO4P → diethyl cyclohexyl(nitro)methylphosphonate (143023-70-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 72h;

DOI:10.1021/ol203132h

Reference yield:

diethyl cyclohexanecarbonylphosphonate (1490-14-8) → diethyl cyclohexyl(nitro)methylphosphonate (143023-70-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine; hydroxylamine hydrochloride / ethanol / 12 h / 20 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 72 h / 20 °C

With pyridine; hydroxylamine hydrochloride; 3-chloro-benzenecarboperoxoic acid; In ethanol; dichloromethane;

DOI:10.1021/ol203132h

upstream raw materials:

triethyl phosphite

diethyl cyclohexanecarbonylphosphonate

cyclohexanylcarbonyl chloride

Downstream raw materials:

((Z)-2-Cyclohexyl-2-nitro-vinyl)-benzene

((Z)-2-Cyclohexyl-2-nitro-vinyl)-benzene

2-((Z)-2-Cyclohexyl-2-nitro-vinyl)-furan

2-((Z)-2-Cyclohexyl-2-nitro-vinyl)-furan

Refernces

• 1、 Fujii, Masayuki. "A New Method for the Preparation of Conjugated Nitro Olefins". . p. 933 - 934. Retrieved 2007/10/02.