Silane, (1,1-dimethylethyl)[(1-ethenylpentyl)oxy]diphenyl-, (S)-

Base Information

• Chemical Name: Silane, (1,1-dimethylethyl)[(1-ethenylpentyl)oxy]diphenyl-, (S)-
• CAS No.: 143264-43-1
• Molecular Formula: C23H32OSi
• Molecular Weight: 352.592
• Mol file: 143264-43-1.mol

Synonyms:

Chemical Property of Silane, (1,1-dimethylethyl)[(1-ethenylpentyl)oxy]diphenyl-, (S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Silane, (1,1-dimethylethyl)[(1-ethenylpentyl)oxy]diphenyl-, (S)-

There total 1 articles about Silane, (1,1-dimethylethyl)[(1-ethenylpentyl)oxy]diphenyl-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(S)-Hept-1-en-3-ol (4938-52-7,67928-91-0,87247-56-1,87247-44-7) + tert-butylchlorodiphenylsilane (58479-61-1) → (3S)-3-tert-butyldiphenylsilyloxy-1-heptene (143264-43-1)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/b917589j

Reference yield:

(3S)-3-tert-butyldiphenylsilyloxy-1-heptene (143264-43-1) → C22H30O2Si

Guidance literature:

(3S)-3-tert-butyldiphenylsilyloxy-1-heptene; With ozone; In dichloromethane; at -78 ℃; for 0.5h;

With dimethylsulfide; In dichloromethane; at 20 ℃;

DOI:10.1039/b917589j

Reference yield:

(3S)-3-tert-butyldiphenylsilyloxy-1-heptene (143264-43-1) → (S)-2-((2R,3S)-2,3-Dihydroxy-heptyl)-piperidine-1-carboxylic acid benzyl ester

Guidance literature:

Multi-step reaction with 3 steps

1: 2.) Bu₄NF / 1.) toluene, reflux, 2.) THF

2: H₂ / PdCl₂ / methanol / 3800 Torr

3: aq. Na₂CO₃ / CH₂Cl₂

With tetrabutyl ammonium fluoride; hydrogen; sodium carbonate; palladium dichloride; In methanol; dichloromethane;

DOI:10.1016/0040-4039(92)80019-G

upstream raw materials:

(S)-Hept-1-en-3-ol

tert-butylchlorodiphenylsilane

Downstream raw materials:

(2S,3aR)-2-[(S)-1-(tert-Butyl-diphenyl-silanyloxy)-pentyl]-hexahydro-isoxazolo[2,3-a]pyridine

(2R,3aS)-2-[(S)-1-(tert-Butyl-diphenyl-silanyloxy)-pentyl]-hexahydro-isoxazolo[2,3-a]pyridine