2,5-Diethyltetrahydrofuran

Base Information

• Chemical Name: 2,5-Diethyltetrahydrofuran
• CAS No.: 41239-48-9
• Molecular Formula: C8H16 O
• Molecular Weight: 128.214
• Hs Code.: 2932190090
• European Community (EC) Number: 255-274-6
• UNII: 4L4S1F79CT
• DSSTox Substance ID: DTXSID70866039
• Nikkaji Number: J89.403F
• Wikidata: Q27259949
• Metabolomics Workbench ID: 43915
• Mol file: 41239-48-9.mol

Synonyms:2,5-Diethyltetrahydrofuran;2,5-diethyloxolane;41239-48-9;Furan, 2,5-diethyltetrahydro-;FEMA No. 3743;EINECS 255-274-6;UNII-4L4S1F79CT;2,5-Diethyltetrahydro-Furan;4L4S1F79CT;2,5-Diethyltetrahydrofurane;2,5-diethyl tetrahydrofuran;SCHEMBL872855;FEMA 3743;DTXSID70866039;AKOS006273070;LS-2665;2,5-DIETHYLTETRAHYDROFURAN [FHFI];Q27259949

Chemical Property of 2,5-Diethyltetrahydrofuran

Chemical Property:

• Appearance/Colour: Colourless liquid; Powerful diffusive sweet-herbaceous carmellic aroma
• Vapor Pressure: 3.82mmHg at 25°C
• Refractive Index: 1.5000 (estimate)
• Boiling Point: 155.9 °C at 760 mmHg
• Flash Point: 39.3 °C
• PSA: 9.23000
• Density: 0.827 g/cm³
• LogP: 2.35400
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 128.120115130
• Heavy Atom Count: 9
• Complexity: 70.6

Purity/Quality:

2,5-Diethyltetrahydrofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Ethers (
• Canonical SMILES: CCC1CCC(O1)CC
• Uses: 2,5-Diethyltetrahydrofuran can be used in analytical and biological studies for enhanced resolution of Mentha piperita volatile fraction using a novel medium-polarity ionic liquid gas chromatography stationary phase.

Technology Process of 2,5-Diethyltetrahydrofuran

There total 3 articles about 2,5-Diethyltetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

octane-3,6-diol (24434-09-1) → 2,5-diethoxytetrahydrofuran (41239-48-9,32101-31-8)

Guidance literature:

With sulfuric acid;

Reference yield:

oct-4-yne-3,6-diol (24434-07-9) → 2,5-diethoxytetrahydrofuran (41239-48-9,32101-31-8)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; ethanol / Hydrogenation

2: aqueous sulfuric acid

With ethanol; sulfuric acid; platinum;

Reference yield:

→ 2,5-diethoxytetrahydrofuran (41239-48-9,32101-31-8)

Guidance literature:

Octan-3-ol, Blei(IV)-tetraacetat;

DOI:10.1016/S0040-4020(01)98365-6

upstream raw materials:

octane-3,6-diol

oct-4-yne-3,6-diol

Downstream raw materials:

1-pyrrol-1-ylbenzimidazole