1-C-ethylaminoadamantane

Base Information

• Chemical Name: 1-C-ethylaminoadamantane
• CAS No.: 26482-53-1
• Molecular Formula: C12H21 N
• Molecular Weight: 179.305
• Hs Code.: 2921300090
• Mol file: 26482-53-1.mol

Synonyms:1-Adamantaneethylamine(8CI); 1-(2-Aminoethyl)adamantane; 2-(1-Adamantyl)ethylamine; Mrz 2/174

Chemical Property of 1-C-ethylaminoadamantane

Chemical Property:

• Vapor Pressure: 0.0249mmHg at 25°C
• Boiling Point: 248°Cat760mmHg
• PKA: 10.94±0.10(Predicted)
• Flash Point: 99.4°C
• PSA: 26.02000
• Density: 1.021g/cm³
• LogP: 3.25190

Purity/Quality:

97% ^*data from raw suppliers

2-((3R,5R,7R)-Adamantan-1-yl)ethan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-C-ethylaminoadamantane

There total 10 articles about 1-C-ethylaminoadamantane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N-(2-adamantan-1-ylethyl)phthalimide → 2-(1-adamantyl)ethanamine (26482-53-1)

Guidance literature:

With hydrazine; In ethanol; for 1h; Heating;

DOI:10.1021/jm070564e

Reference yield:

2-(adamantane-1-yl)ethyl azide (26831-49-2) → 2-(1-adamantyl)ethanamine (26482-53-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid;

DOI:10.1021/jm00288a019

Reference yield:

1-(2-bromo-ethyl)-adamantane (773-37-5) → 2-(1-adamantyl)ethanamine (26482-53-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaN₃ / ethanol / Heating

2: H₂ / PtO₂ / acetic acid

With sodium azide; hydrogen; platinum(IV) oxide; In ethanol; acetic acid;

DOI:10.1021/jm00288a019

upstream raw materials:

1-Carboxymethyladamantane nitrile

2-(1-adamantyl)acetamide

2-(adamantane-1-yl)ethyl azide

1-adamantylacetyl chloride

Downstream raw materials:

(S)-4-(2-Adamantan-1-yl-ethylcarbamoyl)-4-benzyloxycarbonylamino-butyric acid benzyl ester

2-{[2-(1-adamantyl)ethyl]amino}-6-benzyl-5-methylpyrimidin-4(3H)-one

2-(adamantan-1-yl)-N-benzylethan-1-amine