Bis(5-bromo-3-tert-butyl-2-hydroxyphenyl)methanone

Base Information

Chemical Name:Bis(5-bromo-3-tert-butyl-2-hydroxyphenyl)methanone
CAS No.:143445-63-0
Molecular Formula:C21H24Br2O3
Molecular Weight:484.228
Hs Code.:
DSSTox Substance ID:DTXSID601187546
Nikkaji Number:J627.529J
Mol file:143445-63-0.mol

Synonyms:143445-63-0;DTXSID601187546;Bis[5-bromo-3-(1,1-dimethylethyl)-2-hydroxyphenyl]methanone

Suppliers and Price of Bis(5-bromo-3-tert-butyl-2-hydroxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Bis(5-bromo-3-tert-butyl-2-hydroxyphenyl)methanone

Chemical Property:

XLogP3:7.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:484.00717
Heavy Atom Count:26
Complexity:464

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1O)C(=O)C2=C(C(=CC(=C2)Br)C(C)(C)C)O)Br

Technology Process of Bis(5-bromo-3-tert-butyl-2-hydroxyphenyl)methanone

There total 3 articles about Bis(5-bromo-3-tert-butyl-2-hydroxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 143445-65-2
Bis<5-bromo-3-(1,1-dimethylethyl)-2-methoxyphenyl>methanone

: 143445-63-0
Bis<5-bromo-3-(1,1-dimethylethyl)-2-hydroxyphenyl>methanone

Guidance literature:: With boron tribromide; In dichloromethane; 1.) -78 deg C, 1 h, 2.) 25 deg c, 12 h;
DOI:10.1021/jo00104a040

Reference yield:

: Bis-(5-bromo-3-tert-butyl-2-methoxy-phenyl)-methanol

: 143445-63-0
Bis<5-bromo-3-(1,1-dimethylethyl)-2-hydroxyphenyl>methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / CrO₃, Ac₂O

2: 80 percent / BBr₃

With chromium(VI) oxide; acetic anhydride; boron tribromide;
DOI:10.1021/ja00046a061

Reference yield:

: 159390-44-0
1,1'-Methylenebis<5-bromo-3-(1,1-dimethylethyl)-2-methoxybenzene>

: 143445-63-0
Bis<5-bromo-3-(1,1-dimethylethyl)-2-hydroxyphenyl>methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / CrO₃, Ac₂O / 1.) 25 deg C, 12 h, 2.) reflux, 1 h

2: 81 percent / BBr₃ / CH₂Cl₂ / 1.) -78 deg C, 1 h, 2.) 25 deg c, 12 h

With chromium(VI) oxide; acetic anhydride; boron tribromide; In dichloromethane;
DOI:10.1021/jo00104a040