4-(Diethylamino)benzaldehyde thiosemicarbazone

Base Information

• Chemical Name: 4-(Diethylamino)benzaldehyde thiosemicarbazone
• CAS No.: 18300-67-9
• Molecular Formula: C₁₂H₁₈N₄S
• Molecular Weight: 250.368
• NSC Number: 501924
• DSSTox Substance ID: DTXSID80428889
• Mol file: 18300-67-9.mol

Synonyms:18300-67-9;NSC501924;SBB041168;4-(diethylamino)benzaldehyde thiosemicarbazone;DTXSID80428889;STL582549;AKOS000269499;NSC-501924;NCGC00328871-01;AB01322460-02;Z49561509;(2E)-2-[4-(diethylamino)benzylidene]hydrazinecarbothioamide

Chemical Property of 4-(Diethylamino)benzaldehyde thiosemicarbazone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 401.9°Cat760mmHg
• Flash Point: 196.9°C
• Density: 1.13g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 250.12521776
• Heavy Atom Count: 17
• Complexity: 255

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=CC=C(C=C1)C=NNC(=S)N
• Isomeric SMILES: CCN(CC)C1=CC=C(C=C1)/C=N/NC(=S)N

Technology Process of 4-(Diethylamino)benzaldehyde thiosemicarbazone

There total 2 articles about 4-(Diethylamino)benzaldehyde thiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiosemicarbazide (79-19-6) + 4-Diethylaminobenzaldehyde (120-21-8) → 4-diethylamino-benzaldehyde thiosemicarbazone (18300-67-9)

Guidance literature:

With ethanol; water;

Reference yield:

→ 4-diethylamino-benzaldehyde thiosemicarbazone (18300-67-9)

Guidance literature:

/BRN= 3278785/;

DOI:10.1021/jo01353a017

Reference yield: 75.0%

4-diethylamino-benzaldehyde thiosemicarbazone (18300-67-9) + 2-(2-bromoacetyl)-3H-benzo[f]chromen-3-one (88735-43-7) → C27H24N4O2S

Guidance literature:

With sodium acetate; In ethanol; Reflux;

DOI:10.1002/bio.4044

upstream raw materials:

thiosemicarbazide

4-Diethylaminobenzaldehyde

Downstream raw materials:

4-diethylamino-benzaldehyde [4-(1-methyl-1H-benzoimidazol-2-yl)-thiazol-2-yl]-hydrazone