1,3-dibroMo-2-fluorobenzene

Base Information

• Chemical Name: 1,3-dibroMo-2-fluorobenzene
• CAS No.: 1435-54-7
• Molecular Formula: C6H3Br2F
• Molecular Weight: 253.896
• Mol file: 1435-54-7.mol

Synonyms:1,3-dibromo-2-fluorobenzene;

Chemical Property of 1,3-dibroMo-2-fluorobenzene

Chemical Property:

• Melting Point: 53 °C(Solv: acetone (67-64-1))
• Boiling Point: 214.2±20.0 °C(Predicted)
• PSA: 0.00000
• Density: 2.014±0.06 g/cm3(Predicted)
• LogP: 3.35070
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98.5% ^*data from raw suppliers

1,3-Dibromo-2-fluorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-dibroMo-2-fluorobenzene

There total 2 articles about 1,3-dibroMo-2-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

2,6-dibromoaniline (608-30-0) → 1,3-dibromo-2-fluorobenzene (1435-54-7)

Guidance literature:

2,6-dibromoaniline; With hydrogenchloride; sodium nitrite; at 0 - 10 ℃; for 1h;

With ammonium tetrafluroborate; at 0 - 220 ℃; for 3h;

Reference yield:

→ 1,3-dibromo-2-fluorobenzene (1435-54-7)

Guidance literature:

Reference yield: 96.5%

(1H-benzoimidazol-2-yl)phenylamine (21578-58-5) + 1,3-dibromo-2-fluorobenzene (1435-54-7) → N-phenyl-1H-benzimidazol-2-amine

Guidance literature:

With potassium phosphate; In N,N-dimethyl acetamide; at 160 ℃; for 15h; Inert atmosphere;

upstream raw materials:

2,6-dibromoaniline

Downstream raw materials:

5-(5-(3,5-dibromo-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3,3-dimethylbenzo[c][1,2]oxaborol-1(3H)-ol

1,3-dibromo-2-fluoro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene

2-(3,5-dibromo-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Refernces

• 1、 -. "Preparation process of fluorine substituted aromatic compound". . . Retrieved 2008/06/13.