3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)-

Base Information

Chemical Name:3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)-
CAS No.:143570-62-1
Molecular Formula:C17H20N2O
Molecular Weight:268.359
Hs Code.:
DSSTox Substance ID:DTXSID70391295
Nikkaji Number:J1.847.756D
Wikidata:Q82188668
Mol file:143570-62-1.mol

Synonyms:3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)-;143570-62-1;Oprea1_573162;DTXSID70391295;N-tert-Butyl-N-benzylnicotinamide

Suppliers and Price of 3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)-

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:268.157563266
Heavy Atom Count:20
Complexity:315

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)N(CC1=CC=CC=C1)C(=O)C2=CN=CC=C2

Technology Process of 3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)-

There total 1 articles about 3-Pyridinecarboxamide, N-(1,1-dimethylethyl)-N-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20260-53-1
pyridine-3-carbonyl chloride hydrochloride

: 3378-72-1
N-tert-butylbenzylamine

: 143570-62-1
N-benzyl-N-tert-butyl-nicotinamide

Guidance literature:: With pyridine; at 50 ℃; for 2h;
DOI:10.1021/jo00276a039

Reference yield: 80.0%

: 143570-62-1
N-benzyl-N-tert-butyl-nicotinamide

: 79-22-1
methyl chloroformate

: rac-(1S,7aR)-methyl 2-tert-butyl-2,3-dihydro-3-oxo-1-phenyl-1H-pyrrolo[3,4-c]pyridine-5(7aH)-carboxylate

: rac-(1S,7aS)-methyl 2-tert-butyl-2,3-dihydro-3-oxo-1-phenyl-1H-pyrrolo[3,4-c]pyridine-5(7aH)-carboxylate

Guidance literature:: N-benzyl-N-tert-butyl-nicotinamide; With lithium diisopropyl amide; In tetrahydrofuran; at -40 ℃; for 0.166667h;

methyl chloroformate; In tetrahydrofuran;
DOI:10.1021/ol051214u

Reference yield:

: 143570-62-1
N-benzyl-N-tert-butyl-nicotinamide

: 2-tert-butyl-1-phenyl-1,2,3a,7a-tetrahydro-pyrrolo[3,4-c]pyridin-3-one

: 2-tert-butyl-1-phenyl-1,2,5,7a-tetrahydro-pyrrolo[3,4-c]pyridin-3-one

Guidance literature:: N-benzyl-N-tert-butyl-nicotinamide; With lithium diisopropyl amide; In tetrahydrofuran; at -40 ℃; for 0.166667h;

With ammonium chloride; water; In tetrahydrofuran; Title compound not separated from byproducts;
DOI:10.1021/ol051214u