1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE

Base Information

• Chemical Name: 1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE
• CAS No.: 10172-39-1
• Molecular Formula: C₁₄H₉BrO
• Molecular Weight: 273.129
• Hs Code.: 2913000090
• Mol file: 10172-39-1.mol

Synonyms:1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE;1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE 98%

Chemical Property of 1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE

Chemical Property:

• Vapor Pressure: 3.9E-06mmHg at 25°C
• Melting Point: 121-125 °C
• Refractive Index: 1.5400 (estimate)
• Boiling Point: 396.5°Cat760mmHg
• Flash Point: 156.5°C
• PSA: 30.82000
• Density: 1.12g/cm³
• LogP: 2.53290

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE

There total 2 articles about 1-PHENYL-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,7-dimethylbiphenylene (4874-81-1) → 7-Brommethyl-biphenylen-2-aldehyd (10172-39-1)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;

DOI:10.1039/j39660001767

Reference yield:

2-iodo-4,4’-dimethyl-1,1’-biphenyl (14376-77-3) → 7-Brommethyl-biphenylen-2-aldehyd (10172-39-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) AcOOH, Ac₂O, KI, (ii) (pyrolysis), Cu₂O, copper(II) oxalate

2: NBS, (PhCO)2O₂ / CCl₄

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;

DOI:10.1039/j39660001767

upstream raw materials:

2,7-dimethylbiphenylene

2-iodo-4,4’-dimethyl-1,1’-biphenyl