5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid

Base Information

Chemical Name:5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid
CAS No.:143617-90-7
Molecular Formula:C13H17NO4
Molecular Weight:251.282
Hs Code.:
European Community (EC) Number:821-361-8
Mol file:143617-90-7.mol

Synonyms:143617-90-7;5-{[(tert-butoxy)carbonyl]amino}-2-methylbenzoic acid;5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid;2-methyl-5-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic Acid;5-((tert-Butoxycarbonyl)amino)-2-methylbenzoic acid;SCHEMBL4969811;QCOBBPVHVBRAAF-UHFFFAOYSA-N;AKOS012963198;CS-0372304;EN300-192133;5-{[(tert-butoxy)carbonyl]amino}-2-methylbenzoicacid;Z1143322718

Suppliers and Price of 5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:251.11575802
Heavy Atom Count:18
Complexity:321

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)NC(=O)OC(C)(C)C)C(=O)O

Technology Process of 5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid

There total 3 articles about 5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 936129-48-5
methyl 5-((tert-butoxycarbonyl)amino)-2-methylbenzoate

: 143617-90-7
5-<<(1,1-dimethylethoxy)carbonyl>amino>-2-methylbenzoic acid

Guidance literature:: methyl 5-((tert-butoxycarbonyl)amino)-2-methylbenzoate; With methanol; potassium hydroxide; water; In tetrahydrofuran; for 20h;

With hydrogenchloride; In water; pH=4;

Reference yield: 57.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 2840-04-2
5-amino-2-methylbenzoic acid

: 143617-90-7
5-<<(1,1-dimethylethoxy)carbonyl>amino>-2-methylbenzoic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; for 2h;
DOI:10.1002/cmdc.202000548

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1975-52-6
5-nitro-o-toluic acid

: 143617-90-7
5-<<(1,1-dimethylethoxy)carbonyl>amino>-2-methylbenzoic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide; for 2.5h; under 2585.7 Torr;
DOI:10.1021/jm00099a005