Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate

Base Information

Chemical Name:Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate
CAS No.:143619-67-4
Molecular Formula:C14H19NO2
Molecular Weight:233.31
Hs Code.:
DSSTox Substance ID:DTXSID10569052
Wikidata:Q82455753

Synonyms:143619-67-4;Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate;DTXSID10569052

Suppliers and Price of Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:233.141578849
Heavy Atom Count:17
Complexity:259

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1(CCCCC1)C2=CN=CC=C2

Technology Process of Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate

There total 1 articles about Ethyl 1-(pyridin-3-yl)cyclohexane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111-24-0
1,5-dibromo-pentane

: 39931-77-6
pyridin-3-yl-acetic acid ethyl ester

: 143619-67-4
1-(3-pyridyl)cyclohexanecarboxylic acid ethyl ester

Guidance literature:: With potassium tert-butylate; Yield given. Multistep reaction; 1.) DMF, RT, 0.5 h, 2.) DMF, RT, 4 h;
DOI:10.1021/jm00098a004

Reference yield: 36.0%

: 143619-67-4
1-(3-pyridyl)cyclohexanecarboxylic acid ethyl ester

: 143619-73-2
1-(3-pyridyl)cyclohexanecarboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; for 48h; Ambient temperature;
DOI:10.1021/jm00098a004

Reference yield:

: 143619-67-4
1-(3-pyridyl)cyclohexanecarboxylic acid ethyl ester

: 1-Pyridin-3-yl-cyclohexanecarbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 36 percent / aq. NaOH / methanol / 48 h / Ambient temperature

2: SOCl₂, DMF / 1.5 h / Heating

With sodium hydroxide; thionyl chloride; N,N-dimethyl-formamide; In methanol;
DOI:10.1021/jm00098a004