2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine

Base Information

Chemical Name:2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
CAS No.:86029-68-7
Molecular Formula:C₇H₁₁N₃S
Molecular Weight:169.25
Hs Code.:
Mol file:86029-68-7.mol

Synonyms:4H-Thiazolo[4,5-d]azepin-2-amine,5,6,7,8- tetrahydro-;5,6,7,8-Tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine;

Suppliers and Price of 2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
25mg
$ 180.00

TRC
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
250mg
$ 1140.00

Medical Isotopes, Inc.
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
125 mg
$ 2400.00

Medical Isotopes, Inc.
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
25 mg
$ 925.00

Crysdot
5,6,7,8-Tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine 95+%
250mg
$ 392.00

Crysdot
5,6,7,8-Tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine 95+%
1g
$ 980.00

Biosynth Carbosynth
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
100 mg
$ 1050.00

Biosynth Carbosynth
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
250 mg
$ 2100.00

Biosynth Carbosynth
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
25 mg
$ 315.00

Biosynth Carbosynth
2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine
10 mg
$ 178.50

Total 13 raw suppliers

Chemical Property of 2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine

Chemical Property:

Appearance/Colour:Yellow solid
Melting Point:154-159°C
Boiling Point:369.4 °C at 760 mmHg
PKA:9.06±0.20(Predicted)
Flash Point:177.2 °C
PSA：79.18000
Density:1.253 g/cm³
LogP:1.32350
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine

There total 3 articles about 2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83621-33-4
benzyl 4-oxoazepane-1-carboxylate

: 17356-08-0
thiourea

: 86029-68-7
5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-yl-amine

Guidance literature:: benzyl 4-oxoazepane-1-carboxylate; With bromine; In chloroform; at 20 ℃;

thiourea; In ethanol; at 20 ℃; for 2h; Reflux;

With hydrogenchloride; In isopropyl alcohol; for 10h; Reflux;
DOI:10.1039/c9md00379g

Reference yield:

: 31696-09-0
1-benzyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate

: 86029-68-7
5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-yl-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol; water / 2.5 h / Reflux

2.1: bromine / chloroform / 20 °C

2.2: 2 h / 20 °C / Reflux

2.3: 10 h / Reflux

With bromine; potassium hydroxide; In ethanol; chloroform; water; 2.2: |Hantzsch Thiazole Synthesis;
DOI:10.1039/c9md00379g