L-Threonine, N-[N-[N-[N-[(phenylmethoxy)carbonyl]-3-[(phenylmethyl)seleno]-L-alanyl] glycyl]-O-(phenylmethyl)-L-threonyl]-O-(phenylmethyl)-, phenylmethyl ester

Base Information

• Chemical Name: L-Threonine, N-[N-[N-[N-[(phenylmethoxy)carbonyl]-3-[(phenylmethyl)seleno]-L-alanyl] glycyl]-O-(phenylmethyl)-L-threonyl]-O-(phenylmethyl)-, phenylmethyl ester
• CAS No.: 143823-87-4
• Molecular Formula: C₄₉H₅₄N₄O₉Se
• Molecular Weight: 921.949

Synonyms:

Chemical Property of L-Threonine, N-[N-[N-[N-[(phenylmethoxy)carbonyl]-3-[(phenylmethyl)seleno]-L-alanyl] glycyl]-O-(phenylmethyl)-L-threonyl]-O-(phenylmethyl)-, phenylmethyl ester

Chemical Property:

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Technology Process of L-Threonine, N-[N-[N-[N-[(phenylmethoxy)carbonyl]-3-[(phenylmethyl)seleno]-L-alanyl] glycyl]-O-(phenylmethyl)-L-threonyl]-O-(phenylmethyl)-, phenylmethyl ester

There total 1 articles about L-Threonine, N-[N-[N-[N-[(phenylmethoxy)carbonyl]-3-[(phenylmethyl)seleno]-L-alanyl] glycyl]-O-(phenylmethyl)-L-threonyl]-O-(phenylmethyl)-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

benzyl selenol (16645-12-8) + Z-Ser(Tos)-Gly-Thr(Bzl)-Thr(Bzl)-OBzl (143823-86-3) → Z-Sec(Bzl)-Gly-Thr(Bzl)-Thr(Bzl)-OBzl (143823-87-4)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; acetone;

Reference yield:

Z-Sec(Bzl)-Gly-Thr(Bzl)-Thr(Bzl)-OBzl (143823-87-4) → C84H94N8O18Se2 (143823-88-5)

Guidance literature:

With bromine; hydrazine; Yield given. Multistep reaction; 1.) CH₂Cl₂, 15 min;

Reference yield:

Z-Sec(Bzl)-Gly-Thr(Bzl)-Thr(Bzl)-OBzl (143823-87-4) → (2S,3R)-3-Benzyloxy-2-{(2S,3R)-3-benzyloxy-2-[2-((R)-4-benzyloxycarbonylamino-3-oxo-isoselenazolidin-2-yl)-acetylamino]-butyrylamino}-butyric acid benzyl ester (143823-90-9)

Guidance literature:

With bromine; triethylamine; Multistep reaction; 1.) CDCl₃, 15 min;

upstream raw materials:

benzyl selenol

Z-Ser(Tos)-Gly-Thr(Bzl)-Thr(Bzl)-OBzl

Downstream raw materials:

C₈₄H₉₄N₈O₁₈Se₂

(2S,3R)-3-Benzyloxy-2-{(2S,3R)-3-benzyloxy-2-[2-((R)-4-benzyloxycarbonylamino-3-oxo-isoselenazolidin-2-yl)-acetylamino]-butyrylamino}-butyric acid benzyl ester

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