3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2-methyl-6-[4-(2-methyl-1H-imidazo[4,5- c]pyridin-1-yl)phenyl]-, 5-ethyl 3-(2-methoxy-2-oxoethyl) ester

Base Information

Chemical Name:3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2-methyl-6-[4-(2-methyl-1H-imidazo[4,5- c]pyridin-1-yl)phenyl]-, 5-ethyl 3-(2-methoxy-2-oxoethyl) ester
CAS No.:143871-17-4
Molecular Formula:C₃₂H₂₉ClN₄O₆
Molecular Weight:601.058
Hs Code.:
Mol file:143871-17-4.mol

3,5-Pyridinedicarboxylic acid,
4-(2-chlorophenyl)-1,4-dihydro-2-methyl-6-[4-(2-methyl-1H-imidazo[4,5-
c]pyridin-1-yl)phenyl]-, 5-ethyl 3-(2-methoxy-2-oxoethyl) ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2-methyl-6-[4-(2-methyl-1H-imidazo[4,5- c]pyridin-1-yl)phenyl]-, 5-ethyl 3-(2-methoxy-2-oxoethyl) ester

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Technology Process of 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2-methyl-6-[4-(2-methyl-1H-imidazo[4,5- c]pyridin-1-yl)phenyl]-, 5-ethyl 3-(2-methoxy-2-oxoethyl) ester

There total 2 articles about 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2-methyl-6-[4-(2-methyl-1H-imidazo[4,5- c]pyridin-1-yl)phenyl]-, 5-ethyl 3-(2-methoxy-2-oxoethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 143871-08-3
methyl 3-amino-2-butenyl ethanedioate

: 143871-11-8
3-(2-chlorophenyl)-2-ethoxycarbonyl-1-[4-(2-methylimidazo[4,5-c]pyrid-1-yl)phenyl]prop-2-ene-1-one

: 143871-17-4
4-(2-chlorophenyl)-1,4-dihydro-3-ethoxycarbonyl-6-methyl-2-<4-(2-methylimidazo<4,5-c>pyrid-1-yl)phenyl>pyridine-5-methoxycarbonylmethylcarboxylate

Guidance literature:: With acetic acid; In methanol; for 48h; Heating;
DOI:10.1016/S0957-4166(00)80520-0

Reference yield:

: 112641-77-7
2-methoxy-2-oxoethyl3-oxobutanoate

: 143871-17-4
4-(2-chlorophenyl)-1,4-dihydro-3-ethoxycarbonyl-6-methyl-2-<4-(2-methylimidazo<4,5-c>pyrid-1-yl)phenyl>pyridine-5-methoxycarbonylmethylcarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / CH₃COOH, ammonium acetate / toluene / 3.5 h / Heating

2: 51 percent / CH₃COOH / methanol / 48 h / Heating

With ammonium acetate; acetic acid; In methanol; toluene;
DOI:10.1016/S0957-4166(00)80520-0