Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

Base Information

Chemical Name:Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
CAS No.:143878-29-9
Molecular Formula:C12H12ClNO4
Molecular Weight:269.685
Hs Code.:
European Community (EC) Number:604-385-1
DSSTox Substance ID:DTXSID90442854
Mol file:143878-29-9.mol

Synonyms:143878-29-9;Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate;Methyl 4-(acetylamino)-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate;methyl 4-acetamido-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate;Methyl 4-acetamido-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylate;SCHEMBL6600592;DTXSID90442854;Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate;MFCD22381061;AKOS016006851;AC-29986;DS-18454;CS-0153986;FT-0749041;METHYL 5-CHLORO-4-ACETAMIDO-2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXYLATE;Methyl4-(acetylaMino)-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate;7-Benzofurancarboxylic acid, 4-(acetylamino)-5-chloro-2,3-dihydro-, methyl ester

Suppliers and Price of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
250mg
$ 32.00

AK Scientific
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
250mg
$ 43.00

AK Scientific
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
1g
$ 114.00

Alichem
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
5g
$ 330.00

Alichem
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
10g
$ 530.00

Alichem
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
25g
$ 1071.00

Ambeed
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate 97%
1g
$ 74.00

Ambeed
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate 97%
100mg
$ 15.00

Ambeed
Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate 97%
250mg
$ 25.00

American Custom Chemicals Corporation
METHYL-4-ACETAMIDO-5-CHLORO-2,3-DIHYDROBENZOFURAN-7-CARBOXYLATE 95.00%
5MG
$ 500.20

Total 48 raw suppliers

Chemical Property of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:492.027oC at 760 mmHg
PKA:13.17±0.20(Predicted)
Flash Point:251.369oC
PSA：64.63000
Density:1.401g/cm3
LogP:2.09290
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:269.0454856
Heavy Atom Count:18
Complexity:349

Purity/Quality:

99% ^*data from raw suppliers

Methyl4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=C(C=C(C2=C1CCO2)C(=O)OC)Cl

Technology Process of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

There total 15 articles about Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: C₁₂H₁₀ClNO₅

: 143878-29-9
4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid methyl ester

Guidance literature:: With hydrazine hydrate; In ethanol; at 70 - 80 ℃; for 5h;

Reference yield: 85.5%

: methyl 4-acetamido-3-bromo-2-(2-bromoethoxy)-5-chlorobenzoate

: 67-63-0,8013-70-5
isopropyl alcohol

: 143878-29-9
4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid methyl ester

Guidance literature:: methyl 4-acetamido-3-bromo-2-(2-bromoethoxy)-5-chlorobenzoate; With zinc; In N,N-dimethyl acetamide; at 20 - 50 ℃; for 22h; Inert atmosphere;

isopropyl alcohol; With hydrogenchloride; In N,N-dimethyl acetamide; water; at 70 ℃; for 0.5h; Inert atmosphere;