(+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid

Base Information

Chemical Name:(+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid
CAS No.:81645-10-5
Molecular Formula:C₂₃H₁₈N₂O₅
Molecular Weight:402.406
Hs Code.:
Mol file:81645-10-5.mol

Synonyms:

Suppliers and Price of (+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of (+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid

Chemical Property:

PSA：109.61000
LogP:4.41320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid

There total 22 articles about (+)-6-[1-[(2-Hydroxy-6-methylbenzoyl)oxy]ethyl]-1-phenazinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 634205-26-8
6-[1-(2-allyloxy-6-methyl-benzoyloxy)-ethyl]-phenazine-1-carboxylic acid allyl ester

: 81645-10-5,83198-27-0
saphenamycin

: 6-[1-(2-allyloxy-6-methyl-benzoyloxy)-ethyl]-phenazine-1-carboxylic acid

Guidance literature:: With diethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 20 ℃; for 3h;
DOI:10.1016/S0968-0896(02)00472-8

Reference yield:

: 6555-40-4
ethyl 2-hydroxy-6-methylbenzoate

: 81645-10-5,83198-27-0
saphenamycin

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / K₂CO₃ / acetone / 24 h / Heating

2: 98 percent / NaOH / H₂O; ethanol / 30 h / Heating

3: oxalyl chloride; DMF / CH₂Cl₂ / 2 h / 20 °C

4: DMAP; pyridine / 20 °C

5: 61 percent / Et₂NH / Pd(PPh₃)4 / dioxane / 3 h / 20 °C

With pyridine; dmap; sodium hydroxide; oxalyl dichloride; potassium carbonate; diethylamine; N,N-dimethyl-formamide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; dichloromethane; water; acetone;
DOI:10.1016/S0968-0896(02)00472-8

Reference yield:

: 6555-40-4
ethyl 2-hydroxy-6-methylbenzoate

: 81645-10-5,83198-27-0
(S)-6-[1-(2-hydroxy-6-methyl-benzoyloxy)-ethyl]-phenazine-1-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / K₂CO₃ / acetone / 24 h / Heating

2: 98 percent / NaOH / H₂O; ethanol / 30 h / Heating

3: oxalyl chloride; DMF / CH₂Cl₂ / 2 h / 20 °C

4: DMAP; pyridine / 20 °C

5: Et₂NH / Pd(PPh₃)4 / dioxane / 3 h / 20 °C

With pyridine; dmap; sodium hydroxide; oxalyl dichloride; potassium carbonate; diethylamine; N,N-dimethyl-formamide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; dichloromethane; water; acetone;
DOI:10.1016/S0968-0896(02)00472-8