9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

Base Information

Chemical Name:9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine
CAS No.:113852-41-8
Molecular Formula:C₈H₁₃N₆O₄P
Molecular Weight:288.203
Hs Code.:
Mol file:113852-41-8.mol

Synonyms:Phosphonicacid, [[2-(2,6-diamino-9H-purin-9-yl)ethoxy]methyl]- (9CI);9-(2-Phosphonylmethoxyethyl)-2,6-diaminopurine;9-(2-phosphonomethoxyethyl)-2,6-diaminopurine; GS 0573; PMEDAP

Suppliers and Price of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

Chemical Property:

Vapor Pressure:1.51E-23mmHg at 25°C
Boiling Point:748.7°Cat760mmHg
Flash Point:406.6°C
PSA：172.94000
Density:2.03g/cm³
LogP:-0.34620

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

There total 6 articles about 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 207125-88-0
[2-(2,6-Diamino-purin-9-yl)-ethoxymethyl]-phosphonic acid diisopropyl ester

: 113852-41-8
9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

Guidance literature:: With hydrogenchloride; In water; at 130 - 140 ℃; Microwave irradiation; Sealed tube;
DOI:10.1039/c2gc35547g

Reference yield:

: 9-(2-phosphonomethoxyethyl)-2,6-diamino-[8-⁽³⁾H]purine

: 113852-41-8
9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

Guidance literature:: With water; In water-d2; at 20 ℃; pH=7.4; aq. phosphate buffer;
DOI:10.1135/cccc2010020

Reference yield:

: 1904-98-9
2,6-diaminopurine

: 113852-41-8
9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / Sodium hydride / dimethylformamide / 1) 80 deg C for 1 h 2) After addition IIb 80 deg C for 24 h

2: Bromotrimethylsilane / 1) Acetonitrile, room temperature, 2 days 2) aq Et₃N buffer, 30 min

With trimethylsilyl bromide; sodium hydride; In N,N-dimethyl-formamide;