Azathramycin

Base Information

Chemical Name:Azathramycin
CAS No.:76801-85-9
Molecular Formula:C37H70N2O12
Molecular Weight:734.969
Hs Code.:2934990002
European Community (EC) Number:616-385-9
UNII:4LSP9FJT5B
DSSTox Substance ID:DTXSID30998123
Nikkaji Number:J398.492C
Wikidata:Q27260028
ChEMBL ID:CHEMBL1222181
Mol file:76801-85-9.mol

Synonyms:10-dihydro-10-deoxo-11-azaerythromycin A;DD-AZAERYTHROMYCIN A

Suppliers and Price of Azathramycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 97%
50mg
$ 8.00

Ambeed
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 97%
100mg
$ 10.00

Ambeed
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 97%
10mg
$ 6.00

Ambeed
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 97%
5mg
$ 5.00

Usbiological
9-Deoxo-9a-aza-9a-homo erythromycin A
25g
$ 326.00

TRC
9-Deoxo-9a-aza-9a-homoErythromycinA(DesmethylAzithromycin)
100mg
$ 125.00

TRC
9-Deoxo-9a-aza-9a-homoErythromycinA(DesmethylAzithromycin)
1g
$ 425.00

Sigma-Aldrich
Azaerythromycin A
100mg
$ 1260.00

Sigma-Aldrich
Azaerythromycin A Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200?mg
200MG
$ 399.00

DC Chemicals
Azathramycin >98%
1 g
$ 400.00

Total 156 raw suppliers

Chemical Property of Azathramycin

Chemical Property:

Appearance/Colour:White solid
Vapor Pressure:8.8E-31mmHg at 25°C
Melting Point:126-136°C
Refractive Index:1.536
Boiling Point:815.2 °C at 760 mmHg
PKA:13.29±0.70(Predicted)
Flash Point:446.8 °C
PSA：188.87000
Density:1.18 g/cm³
LogP:1.88730
Storage Temp.:-20?C Freezer
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3.6
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:7
Exact Mass:734.49287567
Heavy Atom Count:51
Complexity:1120

Purity/Quality:

99% ^*data from raw suppliers

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1C(C(C(NCC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O
Isomeric SMILES:CC[C@@H]1[C@@]([C@@H]([C@H](NC[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
Uses 9-Deoxo-9a-aza-9a-homo Erythromycin A (Azithromycin EP Impurity A) is a novel intermediate of Azithromycin that acts as antibiotic.

Technology Process of Azathramycin

There total 18 articles about Azathramycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 342371-84-0
9-deoxo-6-deoxy-6,9-epoxy-9,9a-didehydro-9a-aza-homoerythromycin A

: 76801-85-9
9-Deoxo-9a-aza-9a-homoerythromycin A

Guidance literature:: With potassium borohydride; In methanol; at 0 - 5 ℃; for 2h;

Reference yield: 91.5%

: C₃₇H₆₆N₂O₁₂

: 76801-85-9
9-Deoxo-9a-aza-9a-homoerythromycin A

Guidance literature:: C₃₇H₆₆N₂O₁₂; With perchloric acid; hydrogen; platinum on activated charcoal; In methanol; at 5 - 42 ℃; for 3h; under 10298 Torr; pH=5.5;

With sodium hydroxide; In water; pH=12 - 12.5;

Reference yield: 86.6%

: C₃₇H₆₆N₂O₁₂

: 76801-85-9
9-Deoxo-9a-aza-9a-homoerythromycin A

Guidance literature:: C₃₇H₆₆N₂O₁₂; With perchloric acid; hydrogen; platinum on activated charcoal; In methanol; water; at 5 - 42 ℃; for 3h; under 10298 Torr; pH=5.5;

With sodium hydroxide; In water; pH=12 - 12.5; Product distribution / selectivity;