6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Base Information

Chemical Name:6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS No.:144216-11-5
Molecular Formula:C₁₀H₅F₂NO₃
Molecular Weight:225.151
Hs Code.:
DSSTox Substance ID:DTXSID20424502
Nikkaji Number:J1.092.201A,J831.319I
Wikidata:Q82237104
Mol file:144216-11-5.mol

Synonyms:6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;144216-11-5;6,7-difluoro-4-oxo-1H-quinoline-3-carboxylic acid;6,7-Difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid;MFCD04967176;294644-89-6;SBB009385;6,7-difluoro-4-hydroxyquinoline-3-carboxylic acid;SCHEMBL2978428;DTXSID20424502;URJLZNXCWLEREY-UHFFFAOYSA-N;BBL038544;STK312223;AKOS000505698;AKOS016042585;BS-9945;SB70987;CS-0208426;EN300-83643;6,7-difluoro-4-hydroxy-3-quinolinecarboxylic acid;F6548-0034;Z431512458;1,4-Dihydro-6,7-difluoro-4-oxoquinoline-3-carboxylic acid;6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid

Suppliers and Price of 6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+%
5g
$ 658.00

Crysdot
6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+%
10g
$ 942.00

Chemenu
6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95%
10g
$ 888.00

Chemenu
6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95%
5g
$ 622.00

AK Scientific
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
1g
$ 400.00

AK Scientific
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
100mg
$ 179.00

AK Scientific
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
50mg
$ 129.00

AK Scientific
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
20mg
$ 89.00

AK Scientific
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
1mg
$ 39.00

Total 5 raw suppliers

Chemical Property of 6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Chemical Property:

PSA：70.16000
LogP:1.50450
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:225.02374935
Heavy Atom Count:16
Complexity:369

Purity/Quality:

99.90% ^*data from raw suppliers

6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C2C(=CC(=C1F)F)NC=C(C2=O)C(=O)O

Technology Process of 6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

There total 12 articles about 6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 111760-35-1,121873-01-6
ethyl 6,7-difluoro-4-hydroxy-3-quinolinecarboxylate

: 144216-11-5,144216-12-6
6,7-difluoro-4-hydroxyquinoline-3-carboxylic acid

Guidance literature:: With sodium hydroxide; water; at 1 ℃; Heating;
DOI:10.1016/S0022-1139(98)00310-8

Reference yield: 80.0%

: 121873-01-6
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester

: 144216-11-5
6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Guidance literature:: 6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; With water; potassium hydroxide; In tetrahydrofuran; for 4.5h; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; Cooling with ice;