5-Heptenoic acid, 7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen ylthio)methyl]cyclopentyl]-, methyl ester

Base Information

Chemical Name:5-Heptenoic acid, 7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen ylthio)methyl]cyclopentyl]-, methyl ester
CAS No.:144371-34-6
Molecular Formula:C₂₉H₄₆O₆SSi
Molecular Weight:550.832
Hs Code.:
Mol file:144371-34-6.mol

5-Heptenoic acid,
7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen
ylthio)methyl]cyclopentyl]-, methyl ester

Synonyms:

Suppliers and Price of 5-Heptenoic acid, 7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen ylthio)methyl]cyclopentyl]-, methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Heptenoic acid, 7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen ylthio)methyl]cyclopentyl]-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-Heptenoic acid, 7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen ylthio)methyl]cyclopentyl]-, methyl ester

There total 6 articles about 5-Heptenoic acid, 7-[5-(acetyloxy)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[methoxy(phen ylthio)methyl]cyclopentyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64493-06-7
methyl (5Z)-7-iodo-5-heptenoate

: 143261-31-8,143292-00-6,144371-34-6
(Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-(tert-butyl-dimethyl-silanyloxy)-2-(methoxy-phenylsulfanyl-methyl)-cyclopentyl]-hept-5-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1) HMPA, 2) tetramethylethylene diamine (TMEDA) / 1) THF, hexane, -78 deg C, 30 min, 2) -60 deg C, 30 min

2: 73 percent / Bu₄NF, acetic acid / dimethylformamide; H₂O / Ambient temperature

3: 84 percent / DIBAH-BHT / toluene

4: acetylation

With N,N,N,N,N,N-hexamethylphosphoric triamide; N,N,N,N,-tetramethylethylenediamine; 2,6-di-tert-butyl-4-methyl-phenol; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; acetic acid; In water; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4039(00)92528-0

Reference yield:

: 61305-35-9
(R)-4-((tert-butyldimethylsilyl)oxy)cyclopent-2-enone

: 143261-31-8,143292-00-6,144371-34-6
(Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-(tert-butyl-dimethyl-silanyloxy)-2-(methoxy-phenylsulfanyl-methyl)-cyclopentyl]-hept-5-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1) HMPA, 2) tetramethylethylene diamine (TMEDA) / 1) THF, hexane, -78 deg C, 30 min, 2) -60 deg C, 30 min

2: 73 percent / Bu₄NF, acetic acid / dimethylformamide; H₂O / Ambient temperature

3: 84 percent / DIBAH-BHT / toluene

4: acetylation

With N,N,N,N,N,N-hexamethylphosphoric triamide; N,N,N,N,-tetramethylethylenediamine; 2,6-di-tert-butyl-4-methyl-phenol; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; acetic acid; In water; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4039(00)92528-0

Reference yield:

: 87262-37-1
lithium

: 143261-31-8,143292-00-6,144371-34-6
(Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-(tert-butyl-dimethyl-silanyloxy)-2-(methoxy-phenylsulfanyl-methyl)-cyclopentyl]-hept-5-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1) HMPA, 2) tetramethylethylene diamine (TMEDA) / 1) THF, hexane, -78 deg C, 30 min, 2) -60 deg C, 30 min

2: 73 percent / Bu₄NF, acetic acid / dimethylformamide; H₂O / Ambient temperature

3: 84 percent / DIBAH-BHT / toluene

4: acetylation

With N,N,N,N,N,N-hexamethylphosphoric triamide; N,N,N,N,-tetramethylethylenediamine; 2,6-di-tert-butyl-4-methyl-phenol; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; acetic acid; In water; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4039(00)92528-0