2-Morpholinoethanesulfonic acid hydrate

Base Information

• Chemical Name: 2-Morpholinoethanesulfonic acid hydrate
• CAS No.: 145224-94-8
• Molecular Formula: C6H13NO4S^.H2O
• Molecular Weight: 213.25
• Hs Code.: DERIVATION
• European Community (EC) Number: 919-085-9,630-505-7,838-777-0
• DSSTox Substance ID: DTXSID80584934
• Mol file: 145224-94-8.mol

Synonyms:145224-94-8;MES monohydrate;2-Morpholinoethanesulfonic acid hydrate;MES hydrate;1266615-59-1;2-morpholin-4-ylethanesulfonic acid;hydrate;MFCD00149409;4-Morpholineethanesulfonic acid monohydrate;2-Morpholinoethanesulfonicacidxhydrate;2-Morpholinoethanesulfonic acid xhydrate;4-Morpholineethanesulfonic acid, hydrate (1:1);2-(morpholin-4-yl)ethane-1-sulfonic acid hydrate;4-Morpholineethanesulfonic acid, monohydrate;2-(N-Morpholino)ethanesulfonic acid hydrate;4-Morpholineethanesulfonic acid hydrate;2-(n-morpholino)ethanesulfonic acid monohydrate;SCHEMBL108075;MES monohydrate, p.a., 99%;DTXSID80584934;AKOS000503009;4-Morpholinoethanesulfonic acid hydrate;MES hydrate, >=99.5% (titration);4-Morpholineethanesulfonic acid, hydrate;DS-13905;SY010919;2-Morpholinoethane-1-sulfonic acid hydrate;2-morpholinoethanesulfonic acid monohydrate;MES hydrate, BioUltra, >=99.5% (T);4-morpholineethanesulphonic acid monohydrate;4-morpholineethanesulphonic acid-monohydrate;2-(4-Morpholino)ethanesulfonic acid hydrate;2-Morpholin-4-yl-ethanesulfonic acid hydrate;MES monohydrate, BioXtra, >=99.0% (T);F20294;M-3055;M05729;MES hydrate, Vetec(TM) reagent grade, >=99%;MES monohydrate, Vetec(TM) reagent grade, 99%;A889388;2-(Morpholin-4-yl)ethane-1-sulfonic acid--water (1/1);MES monohydrate, BioUltra, for molecular biology, >=99.5% (T);MES hydrate, BioPerformance Certified, suitable for cell culture, >=99.5%;MES hydrate, >=99.5% (titration), pH 2.5-4.0 (0.5 M in H2O), BioXtra

Chemical Property of 2-Morpholinoethanesulfonic acid hydrate

Chemical Property:

• Appearance/Colour: white crystalline powder
• Melting Point: > 300 °C(lit.)
• Boiling Point: 460.9 °C at 760 mmHg
• PKA: 6.1(at 25℃)
• Flash Point: 232.5 °C
• PSA: 84.45000
• Density: 1.349 g/cm³
• LogP: 0.16080
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: H2O: 0.5 M at 20 °C, clear
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 213.06709375
• Heavy Atom Count: 13
• Complexity: 214

Purity/Quality:

≥99.0% ^*data from raw suppliers

MES Monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1COCCN1CCS(=O)(=O)O.O
• Description: MES Monohydrate is a zwitterionic buffer that is not absorbed through cell membranes and is virtually transparent in UV light. MES is a buffering agent used in many biological and biochemical applications. It is also used as a running buffer for denaturing gel electrophoresis. The characteristics of low UV absorptivity, minimal reactivity, stable pH and solubility in water allow MES Monohydrate to be used as a Good's buffer.
• Uses: MES Monohydrate has been used:To adjust the pH of growth medium to 5.5-7.0 in an in vitro cell wall stress assayAs a buffering agent to stabilize enzymatic solutionsAs a component of PAGE running buffer MES monohydrate is a biological buffer often referred to as Good?s buffer. It is useful for cell culture media and protein based buffer formulations to maintain a stable environment in solution. It is also used in the purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors. It is a useful resolving agent for very small proteins on bis-tris gels. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications. MES monohydrate is a buffering agent used in biochemistry and molecular biology that was selected and described by Good et al. It is a zwitterionic, morpholinic buffer that is useful for a pH range of 5.5 – 6.7 and commonly used for cell culture media, as a running buffer in electrophoresis, and for protein purification in chromatography. MES lacks the ability to form a complex with most metal ions and is recommended for use as a non-coordinating buffer in solutions with metal ions. MES is often used in buffered culture media for bacteria, yeast, and mammalian cells. It is toxic towards plants at high concentrations, but can be used in culture media at lower concentrations for plants. Due to low ionic mobility, MES is regarded as an excellent buffer for use in capillary electrochromatography. MES is often employed as a substitute for the highly toxic cacodylate, as well as a substitute for the non-zwitterionic buffers citrate and malate. MES complexes with some organotin(IV) molecules that are being explored as antitumor agents.MES free acid or MES free acid monohydrate can be mixed with MES sodium salt to acquire desired pH. Alternatively, MES free acid or MES free acid monohydrate can be titrated with sodium hydroxide to attain desired pH.