2-(6-Allylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Base Information

Chemical Name:2-(6-Allylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
CAS No.:15763-12-9
Molecular Formula:C13H17N5O4
Molecular Weight:307.31
Hs Code.:
NSC Number:98777
DSSTox Substance ID:DTXSID80935745
ChEMBL ID:CHEMBL46703
Mol file:15763-12-9.mol

Synonyms:N-allyladenosine

Suppliers and Price of 2-(6-Allylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(6-Allylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Chemical Property:

Vapor Pressure:1.4E-17mmHg at 25°C
Melting Point:165-167 °C
Refractive Index:1.749
Boiling Point:646.2°Cat760mmHg
PKA:13.12±0.70(Predicted)
Flash Point:344.6°C
PSA：125.55000
Density:1.67g/cm³
LogP:-0.89130
XLogP3:0.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:307.12805404
Heavy Atom Count:22
Complexity:401

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CCNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O
Uses N-Allyladenosine is a new potential anti-?angiogenic compound that targets human microvascular endothelial cells in vitro.

Technology Process of 2-(6-Allylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

There total 10 articles about 2-(6-Allylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 2004-06-0
6-Chloropurine riboside

: 107-11-9,30551-89-4
1-amino-2-propene

: 15763-12-9
6-N-allyladenosine

Guidance literature:: With triethylamine; In ethanol; for 20h; Heating;
DOI:10.1021/jm00186a031

Reference yield: 70.0%

: N⁶-acetyl-N⁶-allyl-2′,3′,5′-tri-O-acetyladenosine

: 15763-12-9
6-N-allyladenosine

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 48h;
DOI:10.1016/j.ejmech.2014.11.048

Reference yield:

: 58-63-9
Inosine

: 15763-12-9
6-N-allyladenosine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / acetonitrile / 6 h / 0 °C / Reflux

2: ammonia / methanol

3: triethylamine / ethanol / 24 h / 78 °C

With ammonia; triethylamine; In methanol; ethanol; acetonitrile;
DOI:10.1021/jm300917h