Laurdan

Base Information

Chemical Name:Laurdan
CAS No.:74515-25-6
Molecular Formula:C₂₄H₃₅NO
Molecular Weight:353.548
Hs Code.:
UNII:Y97FBL93VW
DSSTox Substance ID:DTXSID80225517
Nikkaji Number:J650.449C
Wikipedia:Laurdan
Wikidata:Q15426238
Mol file:74515-25-6.mol

Synonyms:1-dodecanone, 1-(6-(dimethylamino)-2-naphthalenyl)-;6-dodecanoyl-2-dimethylaminonaphthalene;6-lauroyl-2-dimethylaminonaphthalene;laurdan

Suppliers and Price of Laurdan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine
50mg
$ 925.00

TRC
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine
10mg
$ 220.00

TRC
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine
5mg
$ 115.00

Tocris
Laurdan ≥95%(HPLC)
10
$ 119.00

Sigma-Aldrich
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine suitable for fluorescence, ≥97.0% (HPLC)
100mg
$ 418.00

ChemScene
Laurdan 99.46%
100mg
$ 750.00

ChemScene
Laurdan 99.46%
10mg
$ 160.00

ChemScene
Laurdan 99.46%
5mg
$ 95.00

ChemScene
Laurdan 99.46%
50mg
$ 450.00

Chemenu
1-(6-(Dimethylamino)naphthalen-2-yl)dodecan-1-one 95%
1g
$ 1356.00

Total 12 raw suppliers

Chemical Property of Laurdan

Chemical Property:

Vapor Pressure:4.95E-10mmHg at 25°C
Melting Point:88 °C(lit.)
Boiling Point:497.4°C at 760 mmHg
PKA:4.44±0.40(Predicted)
Flash Point:177.4°C
PSA：20.31000
Density:0.987g/cm³
LogP:7.00940
Storage Temp.:-20°C
Solubility.:DMF: soluble
XLogP3:8.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:12
Exact Mass:353.271864740
Heavy Atom Count:26
Complexity:392

Purity/Quality:

99%, ^*data from raw suppliers

6-Dodecanoyl-N,N-dimethyl-2-naphthylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C
Uses N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasmamembranes. 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine is a fluorescent membrane probe used in phospholipid multilamellar aggregates which distinguishes between phase transitions, phase fluctuations and the coexistence of phase domains. Studies indicate that the bulky and highly hydrated polar head groups of glycosphingolipids interact well with 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine. The fluorescence is derived from the naphthalene moiety, in which a small dipole moment exists due to a partial charge separation between the 2-dimethylamino and the 6-carbonyl residues. This fluorescent tag is ideal to study dipolar relaxation because LAURDAN emits different light depending on the environment it is in. For instance, 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine emits red light in a polar solvent and

Technology Process of Laurdan

There total 1 articles about Laurdan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 222408-62-0
1-(6-methoxy-[2]naphthyl)-dodecan-1-one

: 74515-25-6
laurdan

Guidance literature:: dimethyl amine; With lithium; In N,N,N,N,N,N-hexamethylphosphoric triamide; benzene; for 1h;

1-(6-methoxy-[2]naphthyl)-dodecan-1-one; In N,N,N,N,N,N-hexamethylphosphoric triamide; benzene; at 20 ℃; for 5h;