4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl-

Base Information

Chemical Name:4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl-
CAS No.:144686-14-6
Molecular Formula:C14H25N3O2S
Molecular Weight:299.437
Hs Code.:
DSSTox Substance ID:DTXSID50451043
Nikkaji Number:J501.989C
Mol file:144686-14-6.mol

Synonyms:4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl-;144686-14-6;DTXSID50451043;N-Cyclohexyl-2,2-dimethyl-3-(aminoacetyl)thiazolidine-4-carboxamide

Suppliers and Price of 4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl-

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:299.16674822
Heavy Atom Count:20
Complexity:381

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(N(C(CS1)C(=O)NC2CCCCC2)C(=O)CN)C

Technology Process of 4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl-

There total 3 articles about 4-Thiazolidinecarboxamide, 3-(aminoacetyl)-N-cyclohexyl-2,2-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 144686-19-1
3-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-acetyl]-2,2-dimethyl-thiazolidine-4-carboxylic acid cyclohexylamide

: 144686-14-6
3-(2-Amino-acetyl)-2,2-dimethyl-thiazolidine-4-carboxylic acid cyclohexylamide

Guidance literature:: With hydrazine hydrate; In methanol; at 50 ℃; for 12h;
DOI:10.1055/s-1992-26240

Reference yield: 73.0%

: 66692-88-4
2,2-dimethyl-2,5-dihydrothiazole

: 931-53-3
Cyclohexyl isocyanide

: 6000-43-7
2-aminoethanoic acid hydrochloride

: 144686-14-6
3-(2-Amino-acetyl)-2,2-dimethyl-thiazolidine-4-carboxylic acid cyclohexylamide

Guidance literature:: In methanol; for 0.166667h; Ambient temperature; other 2,5-dihydro-1,3-thiazole, other isocyanide and other aminoacid hydrochloride;
DOI:10.1055/s-1992-26240

Reference yield:

: 931-53-3
Cyclohexyl isocyanide

: 144686-14-6
3-(2-Amino-acetyl)-2,2-dimethyl-thiazolidine-4-carboxylic acid cyclohexylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / methanol / 0 - 15 °C

2: 81 percent / 85percent N₂H₄*H₂O / methanol / 12 h / 50 °C

With hydrazine hydrate; In methanol;
DOI:10.1055/s-1992-26240