Canfosfamide Hydrochloride

Base Information

Chemical Name:Canfosfamide Hydrochloride
CAS No.:439943-59-6
Molecular Formula:C26H41Cl5N5O10PS
Molecular Weight:823.935
Hs Code.:
UNII:1LI341K7NQ
DSSTox Substance ID:DTXSID40963160
Wikidata:Q27252576
NCI Thesaurus Code:C2641
ChEMBL ID:CHEMBL2107319
Mol file:439943-59-6.mol

Synonyms:canfosfamide HCl;gamma-glutamyl-alpha-amino-beta-(2-ethyl-N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidate)sulfonylpropionyl-(R)-(-) phenylglycine;N-(3-((2-((bis(bis(2-chloroethyl)amino)phosphinyl)oxy)ethyl)sulfonyl)-N-glutamyl-alanyl)-2-phenyl-glycine;Telcyta;TER 286;TER-286;TER286;TLK 286;TLK-286;TLK286

Suppliers and Price of Canfosfamide Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CANFOSFAMIDE HYDROCHLORIDE 95.00%
5MG
$ 496.65

Total 2 raw suppliers

Chemical Property of Canfosfamide Hydrochloride

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：250.91000
Density:g/cm³
LogP:6.04030
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:25
Exact Mass:823.072489
Heavy Atom Count:48
Complexity:1130

Purity/Quality:

≥98% ^*data from raw suppliers

CANFOSFAMIDE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(=O)O)NC(=O)C(CS(=O)(=O)CCOP(=O)(N(CCCl)CCCl)N(CCCl)CCCl)NC(=O)CCC(C(=O)O)N.Cl
Isomeric SMILES:C1=CC=C(C=C1)[C@H](C(=O)O)NC(=O)[C@H](CS(=O)(=O)CCOP(=O)(N(CCCl)CCCl)N(CCCl)CCCl)NC(=O)CC[C@@H](C(=O)O)N.Cl
Recent ClinicalTrials:Phase 3 Randomized Study of Telcyta + Doxorubicin Versus Doxorubicin in Platinum Refractory or Resistant Ovarian Cancer
Recent EU Clinical Trials:Phase 3 randomized study of TLK286 (Telcyta?) in combination with liposomal doxorubicin (Doxil?/Caelyx?) versus liposomal doxorubicin (Doxil?/Caelyx?) as second-line therapy in platinum refractory or resistant ovarian cancer

Technology Process of Canfosfamide Hydrochloride

There total 1 articles about Canfosfamide Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: