2-(2-(2-Ethoxyethoxy) ethoxy)ethanamine

Base Information

• Chemical Name: 2-(2-(2-Ethoxyethoxy) ethoxy)ethanamine
• CAS No.: 145373-80-4
• Molecular Formula: C8H19NO3
• DSSTox Substance ID: DTXSID50578840
• Wikidata: Q82469172
• Mol file: 145373-80-4.mol

Synonyms:2-(2-(2-Ethoxyethoxy) ethoxy)ethanamine;145373-80-4;2-(2-(2-ethoxyethoxy)ethoxy)ethanamine;2-[2-(2-Ethoxyethoxy)ethoxy]ethanamine;1-[2-(2-AMINOETHOXY)ETHOXY]-2-ETHOXYETHANE;SCHEMBL2292164;DTXSID50578840;VFA37380;MFCD20696794;AKOS037649496;BT-0121;2-[2-(2-Ethoxyethoxy)ethoxy]ethan-1-amine;EN300-7369704;A920642

Chemical Property of 2-(2-(2-Ethoxyethoxy) ethoxy)ethanamine

Chemical Property:

• XLogP3: -0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 177.13649347
• Heavy Atom Count: 12
• Complexity: 80.7

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOCCOCCOCCN

Technology Process of 2-(2-(2-Ethoxyethoxy) ethoxy)ethanamine

There total 4 articles about 2-(2-(2-Ethoxyethoxy) ethoxy)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(2-(2-(2-ethoxyethoxy)ethoxy)ethyl)isoindoline-1,3-dione (830327-51-0) → 2-(2-(2-ethoxyethoxy)ethoxy)ethan-1-amine (145373-80-4)

Guidance literature:

With hydrazine hydrate; In ethanol; at 76 ℃; for 3h;

DOI:10.1021/jo102358d

Reference yield: 99.1%

1-azide-2-(2-(2-ethoxyethoxy)ethoxy)ethane → 2-(2-(2-ethoxyethoxy)ethoxy)ethan-1-amine (145373-80-4)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; water; at 80 ℃; for 12h;

DOI:10.1039/d1cc05441d

Reference yield: 97.0%

monoethyl ether of triethylene glycol (112-50-5) → 2-(2-(2-ethoxyethoxy)ethoxy)ethan-1-amine (145373-80-4)

Guidance literature:

With 1% Pd on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 2585.81 Torr;

DOI:10.1016/j.poly.2015.09.015

upstream raw materials:

2-(2-(2-(2-ethoxyethoxy)ethoxy)ethyl)isoindoline-1,3-dione

monoethyl ether of triethylene glycol

2-(2-(2-ethoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate