2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]-

Base Information

Chemical Name:2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]-
CAS No.:145439-14-1
Molecular Formula:C11H7F3O2
Molecular Weight:228.171
Hs Code.:
DSSTox Substance ID:DTXSID90570505
Nikkaji Number:J754.019A
Wikidata:Q82457982

Synonyms:145439-14-1;2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]-;SCHEMBL3213139;DTXSID90570505;CZONSUKZOKGQHN-UHFFFAOYSA-N;4-(3-Trifluoromethyl-phenyl)-5H-furan-2-one;4-[3-(Trifluoromethyl)phenyl]furan-2(5H)-one

Suppliers and Price of 2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]-

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:228.03981395
Heavy Atom Count:16
Complexity:320

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=CC(=O)O1)C2=CC(=CC=C2)C(F)(F)F

Technology Process of 2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]-

There total 5 articles about 2(5H)-Furanone, 4-[3-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 56634-50-5
4-bromo-5H-furan-2-one

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 145439-14-1
4-(3-trifluoromethylphenyl)-furan-2(5H)-one

Guidance literature:: With potassium fluoride; tetra-(n-butyl)ammonium iodide; trans-bis(triphenylphosphine)palladium dichloride; In water; toluene; for 12h; Heating / reflux;

Reference yield: 91.0%

: 4-(3-trifluoromethylphenyl)-3-tributylstannylfuran-2(5H)-one

: 145439-14-1
4-(3-trifluoromethylphenyl)-furan-2(5H)-one

Guidance literature:: With trifluoroacetic acid; In methanol; at 20 ℃;
DOI:10.1016/S0040-4020(02)00995-X

Reference yield: 73.0%

: 4508-99-0
methyl γ-hydroxycrotonate

: 454-87-5
3-(trifluoromethyl)benzenediazonium tetrafluoroborate

: 145439-14-1
4-(3-trifluoromethylphenyl)-furan-2(5H)-one

Guidance literature:: With palladium diacetate; In methanol; at 40 ℃; for 5h; regioselective reaction; Inert atmosphere; Darkness;
DOI:10.1055/s-0028-1088132