4-(Aminomethyl)chroman-4-ol

Base Information

Chemical Name:4-(Aminomethyl)chroman-4-ol
CAS No.:146471-52-5
Molecular Formula:C10H13NO2
Molecular Weight:179.22
Hs Code.:2932999099
European Community (EC) Number:835-985-3
DSSTox Substance ID:DTXSID00512850
Mol file:146471-52-5.mol

Synonyms:4-(aminomethyl)chroman-4-ol;146471-52-5;4-(aminomethyl)-2,3-dihydrochromen-4-ol;4-(AMINOMETHYL)-3,4-DIHYDRO-2H-1-BENZOPYRAN-4-OL;2H-1-BENZOPYRAN-4-OL, 4-(AMINOMETHYL)-3,4-DIHYDRO-;4-Aminomethyl-chroman-4-ol;SCHEMBL1333426;SCHEMBL9724427;DTXSID00512850;LJIMCZDPGHYLKP-UHFFFAOYSA-N;WFA47152;AKOS009470630;CS-0106624;FT-0682524;D76657;EN300-234778;F2189-0788

Suppliers and Price of 4-(Aminomethyl)chroman-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(Aminomethyl)chroman-4-ol 95%
5g
$ 945.00

Crysdot
4-(Aminomethyl)chroman-4-ol 95+%
5g
$ 564.00

Chemenu
4-(Aminomethyl)chroman-4-ol 95%
5g
$ 533.00

American Custom Chemicals Corporation
4-(AMINOMETHYL)CHROMAN-4-OL 95.00%
5G
$ 1574.27

Alichem
4-(Aminomethyl)chroman-4-ol
5g
$ 487.60

Alichem
4-(Aminomethyl)chroman-4-ol
1g
$ 155.04

AK Scientific
4-(Aminomethyl)chroman-4-ol
5g
$ 1412.00

Total 18 raw suppliers

Chemical Property of 4-(Aminomethyl)chroman-4-ol

Chemical Property:

Vapor Pressure:2.7E-05mmHg at 25°C
Refractive Index:1.589
Boiling Point:343.4 °C at 760 mmHg
PKA:11.80±0.20(Predicted)
Flash Point:161.5 °C
PSA：55.48000
Density:1.215 g/cm³
LogP:1.31570
Storage Temp.:2-8°C
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

4-(Aminomethyl)chroman-4-ol 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC2=CC=CC=C2C1(CN)O
Uses 4-(Aminomethyl)chroman-4-ol is a reagent used in novel class of transmission blocking antimalarials targeting male gametes.

Technology Process of 4-(Aminomethyl)chroman-4-ol

There total 3 articles about 4-(Aminomethyl)chroman-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74187-63-6
4-((trimethylsilyl)oxy)chroman-4-carbonitrile

: 146471-52-5
(+/-)-4-(aminomethyl)-4-chromanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Heating;
DOI:10.1021/jm00346a012

Reference yield:

: 491-37-2
2,3-dihydro-4H-1-benzopyran-4-one

: 146471-52-5
(+/-)-4-(aminomethyl)-4-chromanol

Guidance literature:: Multi-step reaction with 2 steps

1: ZnI₂ / CH₂Cl₂ / 5 h / 50 - 55 °C

2: LiAlH₄ / tetrahydrofuran / 2 h / Heating

With lithium aluminium tetrahydride; zinc(II) iodide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00346a012