4'-Acetyl-biphenyl-2-carboxylic acid methyl ester

Base Information

Chemical Name:4'-Acetyl-biphenyl-2-carboxylic acid methyl ester
CAS No.:148651-41-6
Molecular Formula:C₁₆H₁₄O₃
Molecular Weight:254.285
Hs Code.:
DSSTox Substance ID:DTXSID80577745
Wikidata:Q82467832
Mol file:148651-41-6.mol

Synonyms:148651-41-6;4'-Acetyl-biphenyl-2-carboxylic acid methyl ester;SCHEMBL5500070;DTXSID80577745;UVCLBHZGBZPGAA-UHFFFAOYSA-N;methyl 4'-acetyl-1,1'-biphenyl-2-carboxylate;Methyl 4'-acetyl[1,1'-biphenyl]-2-carboxylate

Suppliers and Price of 4'-Acetyl-biphenyl-2-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4'-Acetyl-biphenyl-2-carboxylic acid methyl ester

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:254.094294304
Heavy Atom Count:19
Complexity:329

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC=C(C=C1)C2=CC=CC=C2C(=O)OC

Technology Process of 4'-Acetyl-biphenyl-2-carboxylic acid methyl ester

There total 5 articles about 4'-Acetyl-biphenyl-2-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 610-97-9
o-iodo-methyl-benzoic acid

: 149104-90-5
4-acetylphenylboronic acid

: 148651-41-6
4′-acetylbiphenyl-2-carboxylic acid methyl ester

Guidance literature:: o-iodo-methyl-benzoic acid; 4-acetylphenylboronic acid; With sodium carbonate; In tetrahydrofuran; for 0.5h; Inert atmosphere;

With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 60 ℃; for 6h;

Reference yield: 79.0%

: 610-94-6
2-bromobenzoic acid methyl ester

: 149104-90-5
4-acetylphenylboronic acid

: 148651-41-6
4′-acetylbiphenyl-2-carboxylic acid methyl ester

Guidance literature:: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,2-dimethoxyethane; ethanol; at 140 ℃; for 0.416667h;

Reference yield:

: 88-67-5
2-Iodobenzoic acid

: 148651-41-6
4′-acetylbiphenyl-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 2.5 h / 80 °C / Inert atmosphere

2.1: sodium carbonate / tetrahydrofuran / 0.5 h / Inert atmosphere

2.2: 6 h / 60 °C

With sulfuric acid; sodium carbonate; In tetrahydrofuran;