3-(2-Methoxyethoxy)propanoic acid

Base Information

Chemical Name:3-(2-Methoxyethoxy)propanoic acid
CAS No.:149577-05-9
Molecular Formula:C6H12O4
Molecular Weight:148.159
Hs Code.:2918990090
European Community (EC) Number:830-515-3
DSSTox Substance ID:DTXSID60587327
Metabolomics Workbench ID:65009
Nikkaji Number:J22.112K
Wikidata:Q27135721
Mol file:149577-05-9.mol

Synonyms:3-(2-methoxyethoxy)propanoic acid;149577-05-9;m-PEG2-acid;Propanoic acid, 3-(2-methoxyethoxy)-;mPEG2-acid;MFCD09939037;mPEG1-COOH;3-(2-methoxyethoxy)propionic acid;mPEG12-Propionic acid;mPEG1-OCH2CH2COOH;SCHEMBL2461451;CHEBI:67254;3-(2-methoxyethoxy)propanoicacid;DTXSID60587327;KWMXBFIAGYXCCC-UHFFFAOYSA-N;ZFA57705;AKOS000179893;MCULE-5125891492;BP-21571;BS-13237;SY036257;DB-135375;HY-130231;CS-0105847;EN300-55250;C70448;A1-01506;Q27135721;Z316259200

Suppliers and Price of 3-(2-Methoxyethoxy)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2-methoxyethoxy)propanoicacid
50mg
$ 65.00

TRC
3-(2-methoxyethoxy)propanoicacid
25mg
$ 45.00

Iris Biotech GmbH
MeO-EPr-COOH
5 g
$ 837.00

Iris Biotech GmbH
MeO-EPr-COOH
1 g
$ 472.50

Iris Biotech GmbH
MeO-EPr-COOH
100 mg
$ 270.00

dPEG
m-dPEG??-acid
1000 mg
$ 230.00

dPEG
m-dPEG???-acid
1000 mg
$ 515.00

BroadPharm
m-PEG2-acid 98%
5 G
$ 850.00

Apolloscientific
m-PEG2-acid
100mg
$ 273.00

Ambeed
3-(2-Methoxyethoxy)propanoicacid 95%
250mg
$ 156.00

Total 12 raw suppliers

Chemical Property of 3-(2-Methoxyethoxy)propanoic acid

Chemical Property:

Boiling Point:244.2±20.0 °C(Predicted)
PKA:4.28±0.10(Predicted)
PSA：55.76000
Density:1.098±0.06 g/cm3(Predicted)
LogP:0.12410
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:148.07355886
Heavy Atom Count:10
Complexity:91.7

Purity/Quality:

97% ^*data from raw suppliers

3-(2-methoxyethoxy)propanoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCCOCCC(=O)O
Description m-PEG2-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of 3-(2-Methoxyethoxy)propanoic acid

There total 4 articles about 3-(2-Methoxyethoxy)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 109-86-4,95507-80-5
2-methoxy-ethanol

: 140-88-5,9003-32-1
ethyl acrylate

: 149577-05-9,125220-94-2
3-(2-methoxyethyloxy)propionic acid

Guidance literature:: 2-methoxy-ethanol; ethyl acrylate; With potassium carbonate; In acetonitrile; at 90 ℃; for 24h;

With sodium hydroxide; In ethanol; water; at 90 ℃; for 1h;
DOI:10.1016/j.bmc.2016.03.056