2-(Trimethylsilyl)benzene-1,4-diol

Base Information

Chemical Name:2-(Trimethylsilyl)benzene-1,4-diol
CAS No.:15288-57-0
Molecular Formula:C9H14O2Si
Molecular Weight:182.294
Hs Code.:
DSSTox Substance ID:DTXSID40524593
Wikidata:Q82391568
Mol file:15288-57-0.mol

Synonyms:2-trimethylsilylbenzene-1,4-diol;15288-57-0;2-(Trimethylsilyl)benzene-1,4-diol;tms-hydroquinone;DTXSID40524593

Suppliers and Price of 2-(Trimethylsilyl)benzene-1,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(Trimethylsilyl)benzene-1,4-diol

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:182.076306220
Heavy Atom Count:12
Complexity:153

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C)C1=C(C=CC(=C1)O)O

Technology Process of 2-(Trimethylsilyl)benzene-1,4-diol

There total 4 articles about 2-(Trimethylsilyl)benzene-1,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 67289-10-5
1,4-bis(trimethylsilyloxy)-2-bromobenzene

: 15288-57-0
2-trimethylsilyl-1,4-hydroquinone

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1039/c4ob01627k

Reference yield:

: 17863-80-8
1,4-bis(trimethylsilyloxy)-2-trimethylsilylbenzene

: 15288-57-0
2-trimethylsilyl-1,4-hydroquinone

Guidance literature:: With potassium fluoride; Et₃NBn⁽¹⁺⁾Cl^(1-); In dichloromethane; water; acetic acid; for 120h; Ambient temperature;
DOI:10.1002/hlca.19840670529

Reference yield:

: 583-69-7
2-bromobenzene-1,4-diol

: 15288-57-0
2-trimethylsilyl-1,4-hydroquinone

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / 15 h / Heating

2: 1.) BuLi / 1.) Et₂O-hexane, reflux, 3 h; 2.) Et₂O-hexane, roomtemp., 15 h

3: 56 mg / (Et)3NBz(+)*Cl(-), aq. KF / CH₂Cl₂; acetic acid; H₂O / 120 h / Ambient temperature

With potassium fluoride; n-butyllithium; Et₃NBn⁽¹⁺⁾Cl^(1-); In dichloromethane; water; acetic acid;
DOI:10.1002/hlca.19840670529