L-Alanine, N-(3,5-dinitrobenzoyl)-, octyl ester

Base Information

• Chemical Name: L-Alanine, N-(3,5-dinitrobenzoyl)-, octyl ester
• CAS No.: 153169-99-4
• Molecular Formula: C18H25N3O7
• Molecular Weight: 395.412
• Mol file: 153169-99-4.mol

Synonyms:

Chemical Property of L-Alanine, N-(3,5-dinitrobenzoyl)-, octyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-Alanine, N-(3,5-dinitrobenzoyl)-, octyl ester

There total 3 articles about L-Alanine, N-(3,5-dinitrobenzoyl)-, octyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.4%

(S)-octyl 2-aminopropanoate hydrochloride (171963-33-0) + 3,5-dinitrobenoyl chloride (99-33-2) → N-3,5-dinitrobenzoyl-l-alanine octylester (153169-99-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 5h;

DOI:10.1021/ol300684j

Reference yield: 82.0%

3,5-dinitrobenzoic acid (99-34-3) + (S)-octyl 2-aminopropanoate (63907-63-1) → N-3,5-dinitrobenzoyl-l-alanine octylester (153169-99-4)

Guidance literature:

With oxalyl dichloride; triethylamine; In dichloromethane;

DOI:10.1055/s-0035-1560510

Reference yield:

3,5-dinitrobenzoic acid (99-34-3) → N-3,5-dinitrobenzoyl-l-alanine octylester (153169-99-4)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / 5 h / 70 °C

2: triethylamine / dichloromethane / 5 h / 20 °C

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1021/ol300684j

upstream raw materials:

3,5-dinitrobenzoic acid

(S)-octyl 2-aminopropanoate hydrochloride

3,5-dinitrobenoyl chloride

(S)-octyl 2-aminopropanoate

Downstream raw materials:

C₁₈H₂₉N₃O₃