Spiro[4.5]decane-1,4-dione, 8-(1,1-dimethylethyl)-

Base Information

• Chemical Name: Spiro[4.5]decane-1,4-dione, 8-(1,1-dimethylethyl)-
• CAS No.: 154029-97-7
• Molecular Formula: C₁₄H₂₂O₂
• Molecular Weight: 222.327
• DSSTox Substance ID: DTXSID10437540
• Wikidata: Q82253056
• Mol file: 154029-97-7.mol

Synonyms:154029-97-7;Spiro[4.5]decane-1,4-dione, 8-(1,1-dimethylethyl)-;DTXSID10437540

Chemical Property of Spiro[4.5]decane-1,4-dione, 8-(1,1-dimethylethyl)-

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 222.161979940
• Heavy Atom Count: 16
• Complexity: 296

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1CCC2(CC1)C(=O)CCC2=O

Technology Process of Spiro[4.5]decane-1,4-dione, 8-(1,1-dimethylethyl)-

There total 1 articles about Spiro[4.5]decane-1,4-dione, 8-(1,1-dimethylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1'α,4'α)-2-(4-tert-Butyl-1-((trimethylsilyl)oxy)cyclohexyl)-2-((trimethylsilyl)oxy)cyclobutanone → 8-tert-Butylspiro<4.5>decane-1,4-dione (154029-97-7) + (1'α,4'α)-2-(4-tert-Butyl-1-hydroxycyclohexyl)-2-hydroxycyclobutanone

Guidance literature:

With boron trifluoride diethyl etherate; water; In dichloromethane; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00085a041

Reference yield:

8-tert-Butylspiro<4.5>decane-1,4-dione (154029-97-7) → (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-8-tert-butyl-4-oxo-spiro[4.5]dec-1-yl ester

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / baker' syeast, aq. sucrose, Triton X-100 / aq. ethanol / 48 h / 32 °C

2: pyridine / CCl₄ / 72 h / Ambient temperature

With pyridine; baker' syeast; Triton X-100; Sucrose; In tetrachloromethane; ethanol;

DOI:10.1016/0957-4166(96)00430-2