(4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole

Base Information

Chemical Name:(4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole
CAS No.:154132-42-0
Molecular Formula:C13H17NOS
Molecular Weight:235.35
Hs Code.:
DSSTox Substance ID:DTXSID30576208
Nikkaji Number:J601.279E
Wikidata:Q82465778
Mol file:154132-42-0.mol

Synonyms:154132-42-0;DTXSID30576208;(4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole;(S)-4-Isopropyl-2-(2-(methylthio)phenyl)-4,5-dihydrooxazole

Suppliers and Price of (4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:235.10308534
Heavy Atom Count:16
Complexity:265

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1COC(=N1)C2=CC=CC=C2SC
Isomeric SMILES:CC(C)[C@H]1COC(=N1)C2=CC=CC=C2SC

Technology Process of (4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole

There total 1 articles about (4S)-2-[2-(Methylsulfanyl)phenyl]-4-(propan-2-yl)-4,5-dihydro-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 2026-48-4,473-75-6
(S)-valinol

: 6609-54-7
2-cyanothioanisole

: 154132-42-0
(4S)-4-Isopropyl-2-<2-(methylsulfanyl)phenyl>-4,5-dihydro-1,3-oxazole

Guidance literature:: zinc(II) chloride; In chlorobenzene; for 48h; Heating;
DOI:10.1016/S0040-4020(01)80795-X

Reference yield: 94.0%

: 154132-42-0
(4S)-4-Isopropyl-2-<2-(methylsulfanyl)phenyl>-4,5-dihydro-1,3-oxazole

: (S)-4-Isopropyl-2-(2-methanesulfinyl-phenyl)-4,5-dihydro-oxazole

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In chloroform; at -78 ℃; for 1.25h; Product distribution; further reagents, solvents, and temperatures; oxidation of further arylsulfides containing an enantiomerically pure oxazoline in the ortho-position; investigation of the diastereoselectivity;
DOI:10.1016/0040-4039(94)88239-8

Reference yield:

: 154132-42-0
(4S)-4-Isopropyl-2-<2-(methylsulfanyl)phenyl>-4,5-dihydro-1,3-oxazole

: (S)-4-Isopropyl-2-[2-((S)-methanesulfinyl)-phenyl]-4,5-dihydro-oxazole

: (S)-4-Isopropyl-2-[2-((R)-methanesulfinyl)-phenyl]-4,5-dihydro-oxazole

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In chloroform; at -78 ℃; for 1.25h; Product distribution; various oxidants, solvents, temp., and times; also with further sulfides; 1,5- and 1,6-asymmetric induction;
DOI:10.1039/p19960000333