1,3-Benzenedicarboxylic acid, 5,5'-[1,2-phenylenebis(methyleneoxy)]bis-, tetraethyl ester

Base Information

• Chemical Name: 1,3-Benzenedicarboxylic acid, 5,5'-[1,2-phenylenebis(methyleneoxy)]bis-, tetraethyl ester
• CAS No.: 155186-12-2
• Molecular Formula: C32H34O10
• Molecular Weight: 578.616
• Mol file: 155186-12-2.mol

Synonyms:

Chemical Property of 1,3-Benzenedicarboxylic acid, 5,5'-[1,2-phenylenebis(methyleneoxy)]bis-, tetraethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Benzenedicarboxylic acid, 5,5'-[1,2-phenylenebis(methyleneoxy)]bis-, tetraethyl ester

There total 1 articles about 1,3-Benzenedicarboxylic acid, 5,5'-[1,2-phenylenebis(methyleneoxy)]bis-, tetraethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

diethyl 5-hydroxyisophthalate (39630-68-7) + α,α'-dibromo-o-xylene (91-13-4) → α,α'-bis<3,5-bis(dicarbethoxy)phenoxy>-o-xylene (155186-12-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)61420-X

Reference yield: 90.0%

α,α'-bis<3,5-bis(dicarbethoxy)phenoxy>-o-xylene (155186-12-2) → α,α'-bis<3,5-bis(hydroxymethyl)phenoxy>-o-xylene (177798-51-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Heating;

DOI:10.1021/jo950957y

Reference yield:

α,α'-bis<3,5-bis(dicarbethoxy)phenoxy>-o-xylene (155186-12-2) → α,α'-bis<3,5-bis(chloromethyl)phenoxy>-o-xylene (177798-52-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / LAH / tetrahydrofuran / 60 °C

2: 90 percent / SOCl₂; pyridine / CH₂Cl₂

With pyridine; lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.tetlet.2004.12.033

upstream raw materials:

diethyl 5-hydroxyisophthalate

α,α'-dibromo-o-xylene

Downstream raw materials:

α,α'-bis<3,5-bis(hydroxymethyl)phenoxy>-o-xylene

α,α'-bis<3,5-bis(chloromethyl)phenoxy>-o-xylene

α,α'-bis<3,5-bis(mercaptomethyl)phenoxy>-o-xylene

Refernces

• 1、 Rajakumar, Perumal,Dhanasekaran, Manickam,Selvanayagam, Sivashanmugam,Rajakannan, Venkatachalam,Velmurugan, Devadasan,Ravikumar, Krishnan. "Synthesis and structural analysis of isomeric pyridinophanes and thiacyclophanes". . p. 995 - 999. Retrieved 2007/10/03.