Technology Process of 4H-1-Benzopyran-4-one, 5-hydroxy-8-nitro-2-(4-nitrophenyl)-
There total 7 articles about 4H-1-Benzopyran-4-one, 5-hydroxy-8-nitro-2-(4-nitrophenyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
for 3h;
Ambient temperature;
DOI:10.1021/jm00046a020
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 30 percent / nitric acid, glacial acetic acid / 1.) RT, 40 min, 2.) from 45 to 50 deg C, 16 h
2: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, 078 deg C, 2 h, 2.) THF, a) -78 deg C, 1 h, b) RT, 20 h
3: H2SO4, glacial acetic acid / 1 h / 115 - 120 °C
4: 100 percent / boron tribromide / CH2Cl2 / 3 h / Ambient temperature
With
sulfuric acid; nitric acid; boron tribromide; acetic acid; lithium hexamethyldisilazane;
In
dichloromethane;
DOI:10.1021/jm00046a020
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, 078 deg C, 2 h, 2.) THF, a) -78 deg C, 1 h, b) RT, 20 h
2: H2SO4, glacial acetic acid / 1 h / 115 - 120 °C
3: 100 percent / boron tribromide / CH2Cl2 / 3 h / Ambient temperature
With
sulfuric acid; boron tribromide; acetic acid; lithium hexamethyldisilazane;
In
dichloromethane;
DOI:10.1021/jm00046a020
