1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)-

Base Information

Chemical Name:1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)-
CAS No.:159983-42-3
Molecular Formula:C₁₂H₁₅NO₃S
Molecular Weight:253.322
Hs Code.:
DSSTox Substance ID:DTXSID40452246
Wikidata:Q82272746
Mol file:159983-42-3.mol

Synonyms:159983-42-3;1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)-;DTXSID40452246

Suppliers and Price of 1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)-

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:253.07726451
Heavy Atom Count:17
Complexity:391

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CCN(C1CO)S(=O)(=O)C2=CC=CC=C2
Isomeric SMILES:CC1=CCN([C@H]1CO)S(=O)(=O)C2=CC=CC=C2

Technology Process of 1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)-

There total 1 articles about 1H-Pyrrole-2-methanol, 2,5-dihydro-3-methyl-1-(phenylsulfonyl)-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 38066-33-0
triphenyl-vinyl-phosphonium cation

: 88425-34-7
(S)-3-(N-(phenylsulfonyl)amino)-4-hydroxy-2-butanone

: 159983-42-3
((R)-1-Benzenesulfonyl-3-methyl-2,5-dihydro-1H-pyrrol-2-yl)-methanol

Guidance literature:: With sodium hydride; In tetrahydrofuran; acetonitrile; for 2h; Ambient temperature;
DOI:10.1016/0040-4039(94)88236-3

Reference yield: 98.0%

: 159983-42-3
((R)-1-Benzenesulfonyl-3-methyl-2,5-dihydro-1H-pyrrol-2-yl)-methanol

: 159983-54-7
(2S,3S,4R)-1-Benzenesulfonyl-2-hydroxymethyl-3-methyl-pyrrolidine-3,4-diol

Guidance literature:: With osmium(VIII) oxide; trimethylamine-N-oxide;
DOI:10.1016/0040-4039(94)88236-3

Reference yield:

: 159983-42-3
((R)-1-Benzenesulfonyl-3-methyl-2,5-dihydro-1H-pyrrol-2-yl)-methanol

: (2S,3S,4R)-2-Hydroxymethyl-3-methyl-pyrrolidine-3,4-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / OsO₄, Me₃NO

2: 81 percent / Na/NH₃

With osmium(VIII) oxide; trimethylamine-N-oxide; ammonia; sodium;
DOI:10.1016/0040-4039(94)88236-3