2H-Pyran-2-ol, 5,6-dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-

Base Information

Chemical Name:2H-Pyran-2-ol, 5,6-dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-
CAS No.:161676-56-8
Molecular Formula:C₁₅H₂₄O₂
Molecular Weight:236.354
Hs Code.:
Mol file:161676-56-8.mol

Synonyms:

Suppliers and Price of 2H-Pyran-2-ol, 5,6-dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5,6-Dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2H-pyran-2-ol
100mg
$ 725.00

TRC
5,6-Dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2H-pyran-2-ol
10mg
$ 90.00

TRC
5,6-Dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2H-pyran-2-ol
5mg
$ 55.00

AK Scientific
4-Methyl-2-(2,6,6-trimethylcyclohexen-1-yl)-3,6-dihydro-2H-pyran-6-ol
1g
$ 1268.00

Total 1 raw suppliers

Chemical Property of 2H-Pyran-2-ol, 5,6-dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-

Chemical Property:

PSA：29.46000
LogP:3.56660

Purity/Quality:: 5,6-Dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2H-pyran-2-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 5,6-Dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2H-pyran-2-ol is an intermediate used in the synthesis of 9-cis,13-cis-Retinoic Acid (R245015), which is an endogenous retinoid that induces liver fibrosis via the activation of latent transforming growth factor-β. A major plasma metabolite of 9-cis Retinoic Acid (R245000).

Technology Process of 2H-Pyran-2-ol, 5,6-dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-

There total 1 articles about 2H-Pyran-2-ol, 5,6-dihydro-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 638-10-8
ethyl 3-methylbut-2-enoate

: 161676-56-8
C₁₅H₂₄O₂

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 3 h / Reflux

2: zinc / tetrahydrofuran / Reflux; Inert atmosphere

3: diisobutylaluminium hydride / tetrahydrofuran; dichloromethane / -78 - -40 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); diisobutylaluminium hydride; zinc; In tetrahydrofuran; tetrachloromethane; dichloromethane; 2: |Reformatsky Reaction;

Reference yield:

: 161676-56-8
C₁₅H₂₄O₂

: 13312-52-2
9-cis-β-carotene

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogenchloride / 1,2-dichloro-ethane; water / 12.5 h / 40 °C

2.1: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C

2.2: 1 h / -78 - 0 °C

3.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 °C

4.1: methanol / 1 h / 20 °C / Inert atmosphere

5.1: potassium hydroxide / ethanol / 2.25 h / 20 - 70 °C

With hydrogenchloride; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; diisobutylaluminium hydride; potassium hydroxide; In tetrahydrofuran; methanol; ethanol; hexane; water; 1,2-dichloro-ethane; 2.1: |Horner-Wadsworth-Emmons Olefination / 5.1: |Wittig Olefination;

Reference yield:

: 161676-56-8
C₁₅H₂₄O₂

: C₃₈H₄₄P⁽¹⁺⁾*Br^(1-)

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride / 1,2-dichloro-ethane; water / 12.5 h / 40 °C

2.1: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium / tetrahydrofuran; hexane / 0.33 h / 0 °C

2.2: 1 h / -78 - 0 °C

3.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 °C

4.1: methanol / 1 h / 20 °C / Inert atmosphere

With hydrogenchloride; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; diisobutylaluminium hydride; In tetrahydrofuran; methanol; hexane; water; 1,2-dichloro-ethane; 2.1: |Horner-Wadsworth-Emmons Olefination;